Transcription Factor
| Accessions: | UP00081A (UniPROBE 20160601) |
| Names: | A-myb, Amyb, MGC123416, Myb-related protein A, Mybl1, myeloblastosis oncogene-like 1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P51960 |
| Description: | myeloblastosis oncogene-like 1: myeloblastosis oncogene-like 1 (Mybl1), mRNA |
| Length: | 183 |
| Pfam Domains: | 17-63 Myb-like DNA-binding domain 20-80 Myb-like DNA-binding domain 69-115 Myb-like DNA-binding domain 72-130 Myb-like DNA-binding domain 121-165 Myb-like DNA-binding domain 124-177 Myb-like DNA-binding domain |
| Sequence: (in bold interface residues) | 1 HDYEVPQQKGLKKLWNRVKWTRDEDDKLKKLVEQHGTDDWTLIASHLQNRSDFQCQHRWQ 60 61 KVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVK 120 121 KSSWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGI 180 181 KSE |
| Interface Residues: | 17, 52, 53, 56, 57, 60, 61, 62, 103, 104, 105, 106, 108, 109, 113, 114, 121, 141, 150, 155, 156, 157, 159, 160, 161, 163, 164, 165, 168 |
| 3D-footprint Homologues: | 1w0t_A, 5eyb_B, 3osg_A, 7xur_A, 2kdz_A, 1vfc_A, 3zqc_A, 6kks_A, 1mse_C, 1ign_A, 7el3_B |
| Binding Motifs: | UP00081A_1 ttgawAACCGTTAwwhw UP00081A_2 bsaCCAACTGcCgwk |
| Binding Sites: | AAACCGTT AAACGGTT AACCGTCA AACCGTTG AACGGTCA AACGGTCG AACGGTTA AACGGTTC AACGGTTG ACCGTTAA ACCGTTAT ACCGTTGA AGCCGTTA CAACCGTC CAACGGTC CAACTGCC CCAACGGC GACCGTTA GACGGTTA ACCGTTGG |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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