Transcription Factor
Accessions: | O43638 (JASPAR 2024) |
Names: | Forkhead box protein S1, Forkhead-like 18 protein, Forkhead-related transcription factor 10, FOXS1_HUMAN, FREAC-10 |
Organisms: | Homo sapiens |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Uniprot: | O43638 |
Length: | 330 |
Pfam Domains: | 18-113 Fork head domain |
Sequence: (in bold interface residues) | 1 MQQQPLPGPGAPTTEPTKPPYSYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFYRHNRP 60 61 GWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDCHDMFEHGSFLRRRRRFTRQTGA 120 121 EGTRGPAKARRGPLRATSQDPGVPNATTGRQCSFPPELPDPKGLSFGGLVGAMPASMCPA 180 181 TTDGRPRPPMEPKEISTPKPACPGELPVATSSSSCPAFGFPAGFSEAESFNKAPTPVLSP 240 241 ESGIGSSYQCRLQALNFCMGADPGLEHLLASAAPSPAPPTPPGSLRAPLPLPTDHKEPWV 300 301 AGGFPVQGGSGYPLGLTPCLYRTPGMFFFE |
Interface Residues: | 58, 61, 63, 64, 65, 67, 68, 69, 71, 72, 79, 81, 88, 113 |
3D-footprint Homologues: | 3l2c_A, 7vox_H, 2hdc_A, 6ako_C, 7yzg_A, 7tdw_A, 7yz7_A, 6el8_A, 2uzk_A, 7tdx_A, 2a07_J, 7yzb_A, 6nce_A, 3co6_C, 7vou_C, 2c6y_A, 7yze_A, 7cby_C, 3g73_A, 3qrf_G, 4qtr_D |
Binding Motifs: | UN0538.1 wrtGTAAACAdw MA2118.1 tGTAAACA |
Binding Sites: | MA2118.1.4 MA2118.1.18 / MA2118.1.3 MA2118.1.14 MA2118.1.1 / MA2118.1.16 MA2118.1.19 / MA2118.1.20 UN0538.1.1 UN0538.1.10 UN0538.1.11 UN0538.1.12 UN0538.1.13 UN0538.1.14 UN0538.1.15 UN0538.1.16 UN0538.1.17 UN0538.1.18 UN0538.1.19 UN0538.1.2 UN0538.1.20 UN0538.1.3 UN0538.1.4 UN0538.1.5 UN0538.1.6 UN0538.1.7 UN0538.1.8 UN0538.1.9 MA2118.1.13 MA2118.1.10 / MA2118.1.5 / MA2118.1.7 / MA2118.1.9 MA2118.1.11 MA2118.1.12 / MA2118.1.2 MA2118.1.15 MA2118.1.17 MA2118.1.6 MA2118.1.8 |
Publications: | Golson ML, Kaestner KH. Fox transcription factors: from development to disease. Development 143:4558-4570 (2016). [Pubmed] |
Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.