Transcription Factor

						

			
Accessions: 1t2k_C (3D-footprint 20231221)

			
Names: Activator protein 1, AP1, JUN_HUMAN, p39, Proto-oncogene c-Jun, Transcription factor AP-1, V-jun avian sarcoma virus 17 oncogene homolog
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P05412
Length: 62
Pfam Domains:      2-61 bZIP transcription factor
     3-58 Basic region leucine zipper
Sequence: 
(in bold interface residues)		   1 MKAERKRMRNRIAASKSRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKV   60
  61 MN
Interface Residues: 6, 7, 9, 10, 11, 13, 14, 17, 18
3D-footprint Homologues: 1gd2_G, 7x5e_F, 1nwq_C, 2dgc_A, 1dh3_C, 5t01_B, 5vpe_D
Binding Motifs: 1t2k_ABCD TTTAAnTTTnnnnATGTCAA
			
Publications: Panne D, Maniatis T, Harrison S.C. Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer. The EMBO journal 23:4384-93 (2004). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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