Transcription Factor
| Accessions: | UP00357A (UniPROBE 20160601) |
| Names: | HLH-11 |
| Organisms: | Caenorhabditis elegans |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P34474 |
| Description: | Helix Loop Helix Protein 11: none available |
| Length: | 379 |
| Pfam Domains: | 61-111 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 APPSIMSAASAFDLTASGMQNSLRSVLPTSTIGHAPMLANRSLSQPAPLSPTSLDPDRRS 60 61 RRQIANCNERRRMQSINAGFLALRALLPRKEGEKLSKAAILQQTADMVHQLLGHKGEDIP 120 121 DGGEPKKLKLEEDHHDADHQAQIAHLQTILETERAARKALESQVIQLRELLQMTTTSSQA 180 181 SSPVTPRSNGSGGFTLPSSYASSALPTPLRESPERKPSFQDTTSTPLSLLTLNGSPTSSE 240 241 SLASQRIFHPPPTLPSLETTVIRPTPLPPISVEISSPSLSTPSPLTAAPIIFSTAVPTQS 300 301 SILFQTAAAAVTSAMSTGNSTPVALPHHLQGHNSAFVSTQPSLTLSQSMQTIVEAIRHLE 360 361 GSHFIPTSPPPTSQTSLVR |
| Interface Residues: | 62, 64, 65, 66, 68, 69, 72, 73, 97 |
| 3D-footprint Homologues: | 7z5k_B, 1an4_A, 1am9_A, 5i50_B, 6g1l_A, 5eyo_A, 5gnj_I, 7ssa_L |
| Binding Motifs: | UP00357A_1 whyrATCAGCTGatsk |
| Binding Sites: | ATTATAAT TCAGCTGA AACAGCTG AACATATG AATCAGCT ACAGCTGA ACAGCTGG ACAGCTGT ACATATGA ACCAGCTG ATCAGCTG ATCAGGTG ATCATATG CACAGCTG CAGCTGAC CAGCTGAG CAGCTGTA CAGCTGTC CCAGCTGA TCATATGA |
| Publications: | Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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