Transcription Factor
| Accessions: | Q8IUE1 (JASPAR 2024) |
| Names: | Homeobox protein TGIF2LX, TF2LX_HUMAN, TGF-beta-induced transcription factor 2-like protein, TGFB-induced factor 2-like protein, X-linked, TGIF-like on the X |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q8IUE1 |
| Length: | 241 |
| Pfam Domains: | 68-107 Homeobox KN domain 74-107 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MEAAADGPAETQSPVEKDSPAKTQSPAQDTSIMSRNNADTGRVLALPEHKKKRKGNLPAE 60 61 SVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLLQISNWFINARRRILPDMLQQRRNDP 120 121 IIGHKTGKDAHATHLQSTEASVPAKSGPSGPDNVQSLPLWPLPKGQMSREKQPDPESAPS 180 181 QKLTGIAQPKKKVKVSVTSPSSPELVSPEEHADFSSFLLLVDAAVQRAAELELEKKQEPN 240 241 P |
| Interface Residues: | 51, 53, 54, 55, 56, 95, 96, 98, 99, 102, 103, 104, 106, 107 |
| 3D-footprint Homologues: | 6fqp_B, 1mnm_C, 1puf_B, 1le8_B, 2ld5_A, 1k61_B, 1le8_A, 6fqq_E, 1fjl_B, 4xrm_B, 2d5v_B |
| Binding Motifs: | MA1571.1 TGACAgcTGTCA |
| Publications: | Bertolino E., Reimund B., Wildt-Perinic D., Clerc R. G. A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif. J. Biol. Chem. 270:31178-31188 (1995). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.