Transcription Factor
| Accessions: | 1nkp_D (3D-footprint 20231221) |
| Names: | bHLHe39, Class E basic helix-loop-helix protein 39, Myc proto-oncogene protein, MYC_HUMAN, Proto-oncogene c-Myc, Transcription factor p64 |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P01106 |
| Length: | 83 |
| Pfam Domains: | 4-56 Helix-loop-helix DNA-binding domain 57-83 Myc leucine zipper domain |
| Sequence: (in bold interface residues) | 1 MNVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQ 60 61 KLISEEDLLRKRREQLKHKLEQL |
| Interface Residues: | 5, 8, 9, 11, 12, 13, 15, 16, 17, 21, 41 |
| 3D-footprint Homologues: | 1a0a_B, 7z5k_B, 6g1l_A, 7xi3_A, 5i50_B, 7d8t_A, 4zpk_A, 5nj8_D, 7rcu_E, 5eyo_A, 5v0l_A, 1am9_A, 7ssa_L, 5gnj_I, 7xq5_A, 1an4_A |
| Binding Motifs: | 1nkp_DE CACGTGc |
| Publications: | Nair S.K, Burley S.K. X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors. Cell 112:193-205 (2003). [Pubmed] |
| Related annotations: | PaperBLAST |
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