Transcription Factor

Accessions: 1le8_B (3D-footprint 20231221)
Names: Alpha-2 repressor, MATalpha2 protein, Mating-type protein alpha-2, Mating-type protein ALPHA2, MTAL2_YEAST
Organisms: Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P0CY08
Length: 74
Pfam Domains: 4-57 Homeobox domain
16-54 Homeobox KN domain
Sequence:
(in bold interface residues)
1 RGHRFTKENVRILESWFAKNIENPYLDTKGLENLMKNTSLSRIQIKNWVAARRAKEKTIT 60
61 IAPELADLLSGEPL
Interface Residues: 1, 3, 4, 46, 47, 49, 50, 51, 53, 54, 55, 57, 58
3D-footprint Homologues: 2lkx_A, 1mnm_C, 1k61_B, 1le8_B, 1ig7_A, 7q3o_C, 6es3_K, 1puf_B, 7psx_B, 3cmy_A, 6fqp_B, 2hdd_A, 4xrm_B, 6fqq_E, 1du0_A, 5zjt_E, 2hos_A, 6m3d_C
Binding Motifs: 1le8_AB GnAnnannTTACATCA
1le8_B GTAnnr
Binding Sites: 1le8_C
1le8_D
Publications: Ke A, Mathias J.R, Vershon A.K, Wolberger C. Structural and thermodynamic characterization of the DNA binding properties of a triple alanine mutant of MATalpha2. Structure (London, England : 1993) 10:961-71 (2002). [Pubmed]
Related annotations: PaperBLAST

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