Transcription Factor

						

			
Accessions: MSX1_full (HumanTF 1.0)

			
Names: Homeobox protein Hox-7, Homeobox protein MSX-1, Msh homeobox 1-like protein, MSX1, MSX1_HUMAN
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: P28360
Notes: Ensembl ID: ENSG00000163132; Full protein sequence; TF family: homeodomain; Clone source: hORFeome
Length: 304
Pfam Domains:   173-229 Homeobox domain
Sequence: 
(in bold interface residues)		   1 MAPAADMTSLPLGVKVEDSAFGKPAGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLP   60
  61 FSVEALMADHRKPGAKESALAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSV  120
 121 GGLLKLPEDALVKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFT  180
 181 TAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKM  240
 241 AAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMY  300
 301 HLT*
Interface Residues: 171, 173, 174, 175, 176, 214, 215, 217, 218, 221, 222, 224, 225, 226, 229
3D-footprint Homologues: 6fqp_B, 8ejp_B, 1ig7_A, 3cmy_A, 5zfz_A, 1puf_A, 3d1n_M, 8pmf_A, 1fjl_B, 6a8r_A, 2lkx_A, 6m3d_C, 1nk2_P, 1zq3_P, 6es3_K, 7q3o_C, 2ld5_A, 4xrs_G, 2hdd_A, 8osb_E, 4cyc_A, 2r5y_A, 8eml_B, 1jgg_B, 5flv_I, 2hos_A, 5zjt_E, 4j19_B, 1au7_A, 5hod_A, 3lnq_A, 9b8u_A, 3a01_E, 8ik5_C, 7psx_B, 1b72_A, 5jlw_D, 3rkq_B, 7xrc_C, 1e3o_C, 2xsd_C, 1le8_A, 1o4x_A, 1le8_B, 1du0_A, 1mnm_C, 1puf_B, 8g87_X, 1k61_B, 8bx1_A, 4qtr_D
Binding Motifs: MSX1_full syAATTAv
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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