Transcription Factor

Accessions: ZSCAN29 (HT-SELEX2 May2017)
Names: ENSG00000140265, ZSCAN29
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: SCAN_Znf_C2H2 experiment: HT-SELEX Hamming distance: 2 cycle: 3b0, TF family: SCAN_Znf_C2H2 experiment: Methyl-HT-SELEX Hamming distance: 2 cycle: 3b0
Length: 194
Pfam Domains: 7-31 Zinc-finger double domain
19-40 C2H2-type zinc finger
20-42 Zinc finger, C2H2 type
20-42 C2H2-type zinc finger
35-57 Zinc-finger double domain
47-68 C2H2-type zinc finger
48-70 Zinc finger, C2H2 type
48-70 C2H2-type zinc finger
65-86 Zinc-finger double domain
76-98 C2H2-type zinc finger
76-98 Zinc finger, C2H2 type
76-98 C2H2-type zinc finger
91-115 Zinc-finger double domain
104-126 C2H2-type zinc finger
104-126 Zinc finger, C2H2 type
104-124 C2H2-type zinc finger
119-142 Zinc-finger double domain
131-154 C2H2-type zinc finger
132-154 C2H2-type zinc finger
132-154 Zinc finger, C2H2 type
146-170 Zinc-finger double domain
160-178 C2H2-type zinc finger
160-182 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 SFGPNSLLMHQVSHQVENPYKCADCGKSFSRSARLIRHRRIHTGEKPYKCLDCGKSFRDS 60
61 SNFITHRRIHTGEKPYQCGECGKCFNQSSSLIIHQRTHTGEKPYQCEECGKSFNNSSHFS 120
121 AHRRIHTGERPHVCPDCGKSFSKSSDLRAHHRTHTGEKPYGCHDCGKCFSKSSALNKHGE 180
181 IHAREKLLTQSAPK
Interface Residues: 5, 20, 31, 32, 33, 34, 37, 41, 58, 59, 60, 61, 62, 64, 65, 66, 67, 68, 71, 86, 87, 88, 89, 90, 91, 93, 94, 114, 115, 116, 117, 118, 120, 121, 124, 142, 143, 144, 145, 146, 147, 148, 149, 170, 171, 172, 173, 174, 177
3D-footprint Homologues: 5v3j_F, 2kmk_A, 5ei9_F, 1f2i_J, 8ssq_A, 7w1m_H, 5und_A, 8ssu_A, 2i13_A, 5kkq_D, 7eyi_G, 5yel_A, 7n5w_A, 1mey_C, 6wmi_A, 5k5i_A, 2gli_A, 1tf6_A, 6ml4_A, 6blw_A, 8h9h_G, 4m9v_C, 2lt7_A, 2jpa_A, 1ubd_C, 3uk3_C, 1tf3_A, 6jnm_A, 7txc_E, 5kl3_A, 1llm_D, 2wbs_A, 6e94_A, 7ysf_A, 7y3m_I, 6a57_A, 8cuc_F, 6u9q_A, 2drp_D, 1g2f_F, 4x9j_A, 7y3l_A, 5k5l_F, 8gn3_A, 5yj3_D
Binding Motifs: ZSCAN29_2 ccGyrTARmCGKCTAYrCrg
ZSCAN29_methyl_1 cmGyrTAGmCGkCTACACar
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.