Transcription Factor
Accessions: | Q9NHP8 (JASPAR 2024) |
Names: | GTX/Nkx6B-like homeodomain protein, HGTX, HGTX, isoform A, IP01125p, Q9NHP8_DROME, RE53769p |
Organisms: | Drosophila melanogaster |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Uniprot: | Q9NHP8 |
Length: | 513 |
Pfam Domains: | 393-449 Homeobox domain |
Sequence: (in bold interface residues) | 1 MDLINPYMRHHSFAAAAQGSPPSAAQRHHLAAAMSNGFADVHAHAMAAADYQQQLADYHS 60 61 AAAAAAVYANNNNNNNNNSSNNNNSSPLMLLKAAHGGGLKDSDSPSTTPPPASSRLHSDS 120 121 SPSPRYEHNSSPGVDSAKSYALSQRSSGAEDPCQTSESASPPPQGQNDYSPENLSSQRAK 180 181 FQHHHGVNPLALHNANHAGNPGCHNNNNHMDHKLPLSFLGPPLAALHSMTTEMKGQGVGG 240 241 SSASANGLSYSHSPNSHLISDRGSGGSSSSSSTTTTNTNSQGAPNPHGIDTILSKPPPVT 300 301 SAGLSALTGAGIPRFSIAAAAAGMAQYLSQSQGAPLKTHAGHIVDRTHLYWPGLQGLVAN 360 361 PIAWRERLSNTMSANLSQSHQHHPSNDKDGKKKHTRPTFSGQQIFALEKTFEQTKYLAGP 420 421 ERAKLAYALGMSESQVKVWFQNRRTKWRKRHAAEMATAKRKQDDMGGDNDGDCSETMDSD 480 481 NESLDMGESPAQNKRCRSNSSGSSQQQQDNYRH |
Interface Residues: | 307, 312, 314, 316, 351, 393, 394, 395, 396, 434, 435, 437, 438, 441, 442, 445, 446, 449, 459, 462 |
3D-footprint Homologues: | 6fas_B, 1fjl_B, 3d1n_M, 1ig7_A, 2ld5_A, 6a8r_A, 2h1k_B, 1puf_A, 3cmy_A, 5zfz_A, 1nk2_P, 1zq3_P, 2lkx_A, 6es3_K, 7q3o_C, 1puf_B, 5flv_I, 2hos_A, 1b72_A, 5zjt_E, 4cyc_A, 6m3d_C, 5hod_A, 3l1p_A, 3a01_E, 1jgg_B, 7psx_B, 5jlw_D, 3lnq_A, 4xrs_G, 2hdd_A, 1au7_A, 3rkq_B, 2r5y_A, 7xrc_C, 2xsd_C, 1e3o_C, 1le8_A, 1o4x_A, 8g87_X, 1du0_A, 4qtr_D |
Binding Motifs: | MA0191.1 tTAATkR |
Binding Sites: | MA0191.1.15 MA0191.1.8 MA0191.1.3 MA0191.1.1 MA0191.1.10 MA0191.1.11 MA0191.1.12 MA0191.1.13 MA0191.1.14 MA0191.1.16 MA0191.1.17 MA0191.1.18 MA0191.1.19 MA0191.1.2 MA0191.1.20 MA0191.1.4 MA0191.1.5 MA0191.1.6 MA0191.1.7 MA0191.1.9 |
Publications: | Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.