Transcription Factor

Accessions: Q9NUA8 (JASPAR 2024)
Names: ZBT40_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9NUA8
Length: 1239
Pfam Domains: 18-114 BTB/POZ domain
809-830 C2H2-type zinc finger
836-858 C2H2-type zinc finger
836-858 Zinc finger, C2H2 type
851-874 Zinc-finger double domain
865-887 C2H2-type zinc finger
878-903 Zinc-finger double domain
893-915 C2H2-type zinc finger
893-915 Zinc finger, C2H2 type
908-931 Zinc-finger double domain
921-944 Zinc finger, C2H2 type
978-1000 Zinc finger, C2H2 type
978-1000 C2H2-type zinc finger
993-1015 Zinc-finger double domain
1021-1056 Zinc-finger double domain
1047-1069 C2H2-type zinc finger
1135-1158 Zinc finger, C2H2 type
1135-1158 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MELPNYSRQLLQQLYTLCKEQQFCDCTISIGTIYFRAHKLVLAAASLLFKTLLDNTDTIS 60
61 IDASVVSPEEFALLLEMMYTGKLPVGKHNFSKIISLADSLQMFDVAVSCKNLLTSLVNCS 120
121 VQGQVVRDVSAPSSETFRKEPEKPQVEILSSEGAGEPHSSPELAATPGGPVKAETEEAAH 180
181 SVSQEMSVNSPTAQESQRNAETPAETPTTAEACSPSPAVQTFSEAKKTSTEPGCERKHYQ 240
241 LNFLLENEGVFSDALMVTQDVLKKLEMCSEIKGPQKEMIVKCFEGEGGHSAFQRILGKVR 300
301 EESLDVQTVVSLLRLYQYSNPAVKTALLDRKPEDVDTVQPKGSTEEGKTLSVLLLEHKED 360
361 LIQCVTQLRPIMESLETAKEEFLTGTEKRVILNCCEGRTPKETIENLLHRMTEEKTLTAE 420
421 GLVKLLQAVKTTFPNLGLLLEKLQKSATLPSTTVQPSPDDYGTELLRRYHENLSEIFTDN 480
481 QILLKMISHMTSLAPGEREVMEKLVKRDSGSGGFNSLISAVLEKQTLSATAIWQLLLVVQ 540
541 ETKTCPLDLLMEEIRREPGADAFFRAVTTPEHATLETILRHNQLILEAIQQKIEYKLFTS 600
601 EEEHLAETVKEILSIPSETASPEASLRAVLSRAMEKSVPAIEICHLLCSVHKSFPGLQPV 660
661 MQELAYIGVLTKEDGEKETWKVSNKFHLEANNKEDEKAAKEDSQPGEQNDQGETGSLPGQ 720
721 QEKEASASPDPAKKSFICKACDKSFHFYCRLKVHMKRCRVAKSKQVQCKECSETKDSKKE 780
781 LDKHQLEAHGAGGEPDAPKKKKKRLPVTCDLCGREFAHASGMQYHKLTEHFDEKPFSCEE 840
841 CGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSEGKMYACQYCDA 900
901 VFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFHNIEDPYDCKKCRMSFP 960
961 TLQDHRKHIHEVHSKEYHPCPTCGKIFSAPSMLERHVVTHVGGKPFSCGICNKAYQQLSG 1020
1021 LWYHNRTHHPDVFAAQNHRSSKFSSLQCSSCDKTFPNTIEHKKHIKAEHADMKFHECDQC 1080
1081 KELFPTPALLQVHVKCQHSGSQPFRCLYCAATFRFPGALQHHVTTEHFKQSETTFPCELC 1140
1141 GELFTSQAQLDSHLESEHPKVMSTETQAAASQMAQVIQTPEPVAPTEQVITLEETQLAGS 1200
1201 QVFVTLPDSQASQASSELVAVTVEDLLDGTVTLICGEAK
Interface Residues: 818, 819, 820, 821, 824, 825, 828, 846, 847, 849, 850, 851, 852, 853, 854, 855, 856, 859, 874, 875, 876, 877, 878, 880, 881, 885, 903, 904, 905, 906, 907, 909, 910, 914, 931, 932, 933, 934, 935, 937, 938, 942, 961, 963, 964, 967, 969, 970, 988, 989, 991, 992, 994, 995, 1017, 1018, 1019, 1020, 1023, 1026, 1056, 1058, 1059, 1060, 1062, 1063, 1064, 1069, 1084, 1086, 1088, 1089, 1092, 1097, 1114, 1115, 1116, 1117, 1118, 1120, 1121, 1123, 1146, 1148, 1149, 1152, 1174, 1176
3D-footprint Homologues: 1ubd_C, 5k5i_A, 2kmk_A, 7w1m_H, 8ssq_A, 8ssu_A, 4m9v_C, 2gli_A, 7ysf_A, 3uk3_C, 1tf3_A, 7n5w_A, 6jnm_A, 5kl3_A, 7txc_E, 4x9j_A, 2wbs_A, 1tf6_A, 5ei9_F, 1g2f_F, 6e94_A, 6a57_A, 5yel_A, 2jpa_A, 6ml4_A, 6blw_A, 5k5l_F, 5kkq_D, 5yj3_D, 2lt7_A, 1llm_D, 5v3j_F, 6u9q_A, 1f2i_J, 8h9h_G, 7y3m_I, 8cuc_F, 7y3l_A, 8gn3_A, 2drp_D, 8gh6_A
Binding Motifs: UN0146.1 aaAACTTTATTta
UN0146.2 aaAACTTTATT
Binding Sites: UN0146.1.1
UN0146.1.10
UN0146.1.11 / UN0146.1.8
UN0146.1.12 / UN0146.1.9
UN0146.1.13
UN0146.1.10 / UN0146.1.14
UN0146.1.11 / UN0146.1.15
UN0146.1.12 / UN0146.1.16
UN0146.1.13 / UN0146.1.17
UN0146.1.14 / UN0146.1.18
UN0146.1.15 / UN0146.1.19
UN0146.1.2
UN0146.1.20
UN0146.1.3
UN0146.1.4
UN0146.1.5
UN0146.1.5 / UN0146.1.6
UN0146.1.7
UN0146.1.6 / UN0146.1.8
UN0146.1.7 / UN0146.1.9
UN0146.1.16
UN0146.1.17
UN0146.1.18
UN0146.1.19
UN0146.1.20
UN0146.2.1 / UN0146.2.12 / UN0146.2.13 / UN0146.2.17 / UN0146.2.18 / UN0146.2.19 / UN0146.2.2 / UN0146.2.5 / UN0146.2.6
UN0146.2.10
UN0146.2.11
UN0146.2.14 / UN0146.2.15 / UN0146.2.20
UN0146.2.16
UN0146.2.3
UN0146.2.4
UN0146.2.7
UN0146.2.8
UN0146.2.9
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.