Transcription Factor

Accessions: Q8N859 (JASPAR 2024)
Names: ZN713_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q8N859
Length: 443
Pfam Domains: 32-72 KRAB box
281-296 Zinc-finger double domain
285-306 C2H2-type zinc finger
286-308 Zinc finger, C2H2 type
286-308 C2H2-type zinc finger
301-324 Zinc-finger double domain
314-336 C2H2-type zinc finger
314-336 Zinc finger, C2H2 type
314-334 C2H2-type zinc finger
329-353 Zinc-finger double domain
341-364 C2H2-type zinc finger
342-362 C2H2-type zinc finger
342-364 Zinc finger, C2H2 type
356-380 Zinc-finger double domain
369-392 C2H2-type zinc finger
370-392 C2H2-type zinc finger
370-392 Zinc finger, C2H2 type
384-408 Zinc-finger double domain
397-418 C2H2-type zinc finger
398-420 Zinc finger, C2H2 type
398-420 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MPSQNAVFSQEGNMEEEEMNDGSQMVRSQESLTFQDVAVDFTREEWDQLYPAQKNLYRDV 60
61 MLENYRNLVALGYQLCKPEVIAQLELEEEWVIERDSLLDTHPDGENRPEIKKSTTSQNIS 120
121 DENQTHEMIMERLAGDSFWYSILGGLWDFDYHPEFNQENHKRYLGQVTLTHKKITQERSL 180
181 ECNKFAENCNLNSNLMQQRIPSIKIPLNSDTQGNSIKHNSDLIYYQGNYVRETPYEYSEC 240
241 GKIFNQHILLTDHIHTAEKPSECGKAFSHTSSLSQPQMLLTGEKPYKCDECGKRFSQRIH 300
301 LIQHQRIHTGEKPFICNGCGKAFRQHSSFTQHLRIHTGEKPYKCNQCGKAFSRITSLTEH 360
361 HRLHTGEKPYECGFCGKAFSQRTHLNQHERTHTGEKPYKCNECGKAFSQSAHLNQHRKIH 420
421 TREKLCEYKCEQTVRHSPSFSST
Interface Residues: 211, 214, 217, 218, 220, 221, 224, 227, 246, 247, 248, 249, 252, 269, 271, 272, 275, 296, 297, 299, 300, 303, 307, 314, 325, 326, 327, 328, 330, 331, 333, 334, 335, 337, 352, 353, 354, 355, 356, 357, 358, 359, 380, 381, 382, 383, 384, 386, 387, 388, 408, 409, 410, 411, 412, 413, 414, 415, 416
3D-footprint Homologues: 8ssq_A, 8ssu_A, 5v3j_F, 5yel_A, 1tf6_A, 2i13_A, 7w1m_H, 6jnm_A, 5kkq_D, 5ei9_F, 5kl3_A, 6wmi_A, 5und_A, 6a57_A, 2kmk_A, 6ml4_A, 6blw_A, 7txc_E, 5k5i_A, 2gli_A, 7eyi_G, 6e94_A, 7ysf_A, 2jpa_A, 1ubd_C, 7n5w_A, 1tf3_A, 4x9j_A, 8gn3_A, 6u9q_A, 1mey_C, 2drp_D, 1f2i_J, 1g2f_F, 5k5l_F, 8h9h_G, 2lt7_A, 7y3l_A, 3uk3_C, 8cuc_F, 1llm_D, 2wbs_A, 4m9v_C, 7y3m_I, 5yj3_D
Binding Motifs: UN0217.1 tmGACGACTGCCACGAAAs
UN0216.1 taGAAAAAAGACwrGAAAg
UN0216.2 aGAAAAAAGACwrGAAA
UN0217.2 mGACGACTGCCACGAAA
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.