Transcription Factor

Accessions: Q4H303 (JASPAR 2024)
Names: Otx, Q4H303_CIOIN, Transcription factor protein
Organisms: Ciona intestinalis
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q4H303
Length: 425
Pfam Domains: 66-122 Homeobox domain
Sequence:
(in bold interface residues)
1 MSYLKSPHYAMNGLGLGHDMNLLHPTVTYPGDSAACYFQRIQGMHQGAKNMQFAAPPVYS 60
61 SSRKQRRERTTFTRAQLDILEALFGKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 120
121 RQQVQQQQQKQKSGSGGSSSNSSSSTGSSSSGSASSTNSNNNSSSSSNKKKSPPTTPTPT 180
181 ANGPTTSSSPFQQHGAPSAHAPHAQSTSPPLPSSPVSSNGQIAPSVTPSELMSANGPAPI 240
241 SLPGSHGAHSGMVHNGSSSNIWSPASVSPGASSDGASNVPGIGYTGALGSNNSPYMAAAA 300
301 AVAHAAHSPYSATSNAQVSSTGYPQNYHTSHSYFGTMEASYLPSVPFPGAAPGCGMGDMS 360
361 MAGQQSAAQLGHHGTGQPHPASHHQFMSQSYPYHHASSGVTPTYPTVSDCLDYKDQTQAW 420
421 KFQVL
Interface Residues: 34, 35, 36, 37, 39, 40, 43, 46, 47, 50, 65, 66, 67, 68, 69, 107, 108, 110, 111, 114, 115, 117, 118, 119, 121, 122
3D-footprint Homologues: 1o4x_A, 1e3o_C, 1au7_A, 8bx1_A, 4j19_B, 3d1n_M, 8ejp_B, 1fjl_B, 6a8r_A, 8pmf_A, 1ig7_A, 3cmy_A, 5zfz_A, 1puf_A, 3lnq_A, 1nk2_P, 1zq3_P, 1jgg_B, 2lkx_A, 6m3d_C, 7q3o_C, 2ld5_A, 6es3_K, 2hdd_A, 5zjt_E, 2r5y_A, 1puf_B, 8osb_E, 7psx_B, 5hod_A, 2hos_A, 8eml_B, 1b72_A, 3a01_E, 5jlw_D, 3rkq_B, 4xrs_G, 2d5v_B, 9b8u_A, 4cyc_A, 8ik5_C, 5flv_I, 1le8_A, 4qtr_D, 8g87_X, 1du0_A
Binding Motifs: MA1908.1 wwwmrvmtTAATCCgmwwwwwh
MA1908.2 tTAATCCg
Publications: Roure A, Lemaire P, Darras S. An otx/nodal regulatory signature for posterior neural development in ascidians. PLoS Genet : (2014). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.