Transcription Factor

Accessions: 5hlg_A (3D-footprint 20231221)
Names: MarR family transcriptional regulator, Q5HKZ1_STAEQ
Organisms: Staphylococcus epidermidis, strain ATCC 35984 / RP62A
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q5HKZ1
Length: 134
Pfam Domains: 29-86 Sugar-specific transcriptional regulator TrmB
33-91 MarR family
34-100 Winged helix DNA-binding domain
34-91 MarR family
39-107 HxlR-like helix-turn-helix
47-88 FeoC like transcriptional regulator
57-103 Transcriptional regulator PadR-like family
Sequence:
(in bold interface residues)
1 QEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHL 60
61 DLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLETKYV 120
121 FEELEQTLKHLIEK
Interface Residues: 54, 63, 64, 65, 66, 68, 69, 70, 72, 73, 90
3D-footprint Homologues: 7el3_B, 7dvv_A, 5yi2_J, 5h3r_A, 1z9c_A, 6c2s_C, 3q5f_A, 4lln_I, 5f7q_C, 4aik_A, 4fx4_B, 5hlg_E, 3zpl_B, 5hso_A, 6jbx_A
Binding Motifs: 5hlg_AC CGATTnAGnnnncTnaATCG
Publications: Liu G, Liu X, Xu H, Liu X, Zhou H, Huang Z, Gan J, Chen H, Lan L, Yang CG. Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J Am Chem Soc 139:1598-1608 (2017). [Pubmed]
Related annotations: PaperBLAST

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