Transcription Factor
Accessions: | NFKB2 (HT-SELEX2 May2017) |
Names: | ENSG00000077150, NFKB2 |
Organisms: | Homo sapiens |
Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
Notes: | TF family: RHD_IPT experiment: HT-SELEX Hamming distance: 1 cycle: 4, TF family: RHD_IPT experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 4 |
Length: | 332 |
Pfam Domains: | 24-204 Rel homology domain (RHD) |
Sequence: (in bold interface residues) | 1 DFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKT 60 61 YPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNL 120 121 GVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMDLSIVRLRFSA 180 181 FLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKD 240 241 DIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGD 300 301 VSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQ |
Interface Residues: | 36, 38, 39, 41, 42, 44, 45, 46, 205, 207, 236, 267 |
3D-footprint Homologues: | 1nfk_A, 1a3q_A, 2o61_A, 1gji_A, 2ram_A, 1imh_C, 7cli_B |
Binding Motifs: | NFKB2_2 rGGGGAWgymCCk NFKB2_methyl_1 aGGGrAWkyMCCk |
Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.