Transcription Factor

Accessions: Q8N4W9 (JASPAR 2024)
Names: ZN808_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q8N4W9
Length: 903
Pfam Domains: 24-61 KRAB box
246-270 Zinc-finger double domain
259-281 C2H2-type zinc finger
274-298 Zinc-finger double domain
286-299 C2H2-type zinc finger
287-309 Zinc finger, C2H2 type
301-325 Zinc-finger double domain
314-334 C2H2-type zinc finger
315-337 Zinc finger, C2H2 type
315-337 C2H2-type zinc finger
329-353 Zinc-finger double domain
342-365 C2H2-type zinc finger
343-365 Zinc finger, C2H2 type
343-365 C2H2-type zinc finger
357-382 Zinc-finger double domain
370-385 C2H2-type zinc finger
386-410 Zinc-finger double domain
398-414 C2H2-type zinc finger
399-421 Zinc finger, C2H2 type
399-418 C2H2-type zinc finger
413-437 Zinc-finger double domain
426-447 C2H2-type zinc finger
427-449 C2H2-type zinc finger
427-449 Zinc finger, C2H2 type
442-466 Zinc-finger double domain
455-477 C2H2-type zinc finger
470-494 Zinc-finger double domain
482-506 C2H2-type zinc finger
483-505 Zinc finger, C2H2 type
498-522 Zinc-finger double domain
510-533 C2H2-type zinc finger
511-533 C2H2-type zinc finger
511-533 Zinc finger, C2H2 type
525-548 Zinc-finger double domain
539-557 C2H2-type zinc finger
539-549 C2H2-type zinc finger
539-561 Zinc finger, C2H2 type
554-577 Zinc-finger double domain
566-589 C2H2-type zinc finger
567-589 Zinc finger, C2H2 type
567-589 C2H2-type zinc finger
581-605 Zinc-finger double domain
594-615 C2H2-type zinc finger
595-617 Zinc finger, C2H2 type
595-615 Zinc-finger of C2H2 type
595-617 C2H2-type zinc finger
609-633 Zinc-finger double domain
623-645 Zinc finger, C2H2 type
638-662 Zinc-finger double domain
650-673 C2H2-type zinc finger
651-673 Zinc finger, C2H2 type
651-673 C2H2-type zinc finger
665-690 Zinc-finger double domain
679-693 C2H2-type zinc finger
696-718 Zinc-finger double domain
706-727 C2H2-type zinc finger
707-729 Zinc finger, C2H2 type
707-729 C2H2-type zinc finger
721-745 Zinc-finger double domain
734-757 C2H2-type zinc finger
735-757 Zinc finger, C2H2 type
750-774 Zinc-finger double domain
762-785 C2H2-type zinc finger
763-785 Zinc finger, C2H2 type
777-801 Zinc-finger double domain
791-813 C2H2-type zinc finger
791-807 C2H2-type zinc finger
791-813 Zinc finger, C2H2 type
806-829 Zinc-finger double domain
818-831 C2H2-type zinc finger
819-841 Zinc finger, C2H2 type
819-839 C2H2-type zinc finger
833-858 Zinc-finger double domain
846-857 C2H2-type zinc finger
847-869 Zinc finger, C2H2 type
847-869 C2H2-type zinc finger
847-865 Zinc-finger of C2H2 type
861-885 Zinc-finger double domain
874-894 C2H2-type zinc finger
875-897 Zinc finger, C2H2 type
875-897 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MLREEAAQKRKGKESGMALPQGRLTFRDVAIEFSLAEWKFLNPAQRALYREVMLENYRNL 60
61 EAVDISSKHMMKEVLSTGQGNREVIHTGTLQRHQSYHIGDFCFQEIEKEIHNIEFQCQED 120
121 ERNGHEAPTTKIKKLTGSTDQHDHRHAGNKPIKDQLGSSFYSHLPELHIFQIKGEIANQL 180
181 EKSTSDASSVSTSQRISCRPQIHISNNYGNNPLNSSLLPQKQEVHMREKSFPCNESGKAF 240
241 NCSSLLRKHQIPHLGDKQYKCDVCGKLFNHKQYLACHRRCHTGEKPYKCKECGKSFSYKS 300
301 SLTCHHRLHTGVKPYKCNECGKVFRQNSALVIHKAIHTGEKPYKCNECGKAFNQQSHLSR 360
361 HQRLHTGVKPYKCKICEKAFACHSYLANHTRIHSGEKTYKCNECGKAFNHQSSLARHHIL 420
421 HTGEKPYKCEECDKVFSQKSTLERHKRIHTGEKPYKCKVCDTAFTCNSQLARHRRIHTGE 480
481 KTYKCNECRKTFSRRSSLLCHRRLHSGEKPYKCNQCGNTFRHRASLVYHRRLHTLEKSYK 540
541 CTVCNKVFMRNSVLAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHRRLHTGEKPYKCEAC 600
601 DKVFGQKSALESHKRIHTGEKPYRCQVCDTAFTWNSQLARHTRIHTGEKTYKCNECGKTF 660
661 SYKSSLVWHRRLHGGEKSYKCKVCDKAFVCRSYVAKHTRIHSGMKPYKCNECSKTFSNRS 720
721 SLVCHRRIHSGEKPYKCSECSKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFRHWSSLVY 780
781 HRRLHTGEKSYKCTVCDKAFVRNSYLARHIRIHTAEKPYKCNECGKAFNEQSHLSRHHRI 840
841 HTGEKPYKCEACDKVFSRKSHLKRHRIIHTGEKPYKCNECGKAFSDRSTLIHHQAIHGIG 900
901 KFD
Interface Residues: 269, 270, 272, 273, 276, 298, 300, 301, 304, 325, 326, 327, 328, 329, 331, 332, 333, 334, 335, 338, 354, 355, 356, 357, 358, 360, 361, 381, 382, 383, 384, 385, 388, 391, 409, 410, 411, 412, 413, 415, 416, 419, 438, 440, 441, 444, 465, 466, 467, 468, 469, 472, 494, 496, 497, 500, 522, 523, 524, 525, 527, 528, 530, 539, 550, 551, 552, 553, 556, 562, 576, 577, 578, 580, 581, 584, 588, 605, 606, 607, 608, 609, 611, 612, 633, 634, 635, 636, 637, 639, 640, 662, 663, 664, 665, 667, 668, 690, 691, 718, 720, 721, 749, 774, 776, 777, 780, 784, 801, 802, 804, 805, 808, 830, 831, 832, 833, 835, 836, 857, 858, 859, 860, 861, 862, 863, 864, 885, 886, 887, 888, 889
3D-footprint Homologues: 6jnm_A, 5ei9_F, 7y3l_A, 8cuc_F, 1tf6_A, 7txc_E, 5v3j_F, 6u9q_A, 4m9v_C, 2jpa_A, 5yj3_D, 5kl3_A, 6ml4_A, 7w1m_H, 8ssu_A, 8ssq_A, 1f2i_J, 5k5i_A, 7n5w_A, 8h9h_G, 2kmk_A, 7ysf_A, 3uk3_C, 6blw_A, 6e94_A, 1g2f_F, 7y3m_I, 6a57_A, 2drp_D, 5yel_A, 2gli_A, 5kkq_D, 1tf3_A, 4x9j_A, 1ubd_C, 2wbs_A, 8gn3_A, 1llm_D, 2lt7_A, 5k5l_F
Binding Motifs: UN0234.1 GgAGGTCTATAAAykG
Binding Sites: UN0234.1.1
UN0234.1.10 / UN0234.1.7
UN0234.1.11
UN0234.1.12
UN0234.1.13 / UN0234.1.8
UN0234.1.14
UN0234.1.15
UN0234.1.16
UN0234.1.17 / UN0234.1.9
UN0234.1.10 / UN0234.1.18
UN0234.1.11 / UN0234.1.19
UN0234.1.1 / UN0234.1.2
UN0234.1.12 / UN0234.1.20
UN0234.1.2 / UN0234.1.3
UN0234.1.3 / UN0234.1.4
UN0234.1.4 / UN0234.1.5
UN0234.1.5 / UN0234.1.6
UN0234.1.6 / UN0234.1.7
UN0234.1.8
UN0234.1.9
UN0234.1.13
UN0234.1.14
UN0234.1.15
UN0234.1.16
UN0234.1.17
UN0234.1.18
UN0234.1.19
UN0234.1.20
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.