Transcription Factor

						

			
Accessions: MYF6_full (HumanTF 1.0)

			
Names: bHLHc4, Class C basic helix-loop-helix protein 4, Muscle-specific regulatory factor 4, Myf-6, MYF6, MYF6_HUMAN, Myogenic factor 6
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: P23409
Notes: Ensembl ID: ENSG00000111046; Full protein sequence; TF family: bHLH; Clone source: GrLR3
Length: 243
Pfam Domains:      3-93 Myogenic Basic domain
   94-145 Helix-loop-helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 MMMDLFETGSYFFYLDGENVTLQPLEVAEGSPLYPGSDGTLSPCQDQMPPEAGSDSSGEE   60
  61 HVLAPPGLQPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRERRRLKKINEAFEALKRRT  120
 121 VANPNQRLPKVEILRSAISYIERLQDLLHRLDQQEKMQELGVDPFSYRPKQENLEGADFL  180
 181 RTCSSQWPSVSDHSRGLVITAKEGGASIDSSASSSLRCLSSIVDSISSEERKLPCVEEVV  240
 241 EK*
Interface Residues: 95, 99, 101, 102, 105, 106
3D-footprint Homologues: 7z5k_B, 8osb_B, 7d8t_A
Binding Motifs: MYF6_full AACArCTGTY
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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