Transcription Factor
| Accessions: | O14771 (JASPAR 2024) |
| Names: | Putative transcription factor CR53, Zinc finger protein 213, Zinc finger protein with KRAB and SCAN domains 21, ZN213_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | O14771 |
| Length: | 459 |
| Pfam Domains: | 40-132 SCAN domain 202-239 KRAB box 317-339 Zinc finger, C2H2 type 317-339 C2H2-type zinc finger 317-339 C2H2-type zinc finger 331-355 Zinc-finger double domain 344-363 C2H2-type zinc finger 345-367 Zinc finger, C2H2 type 345-367 C2H2-type zinc finger 359-384 Zinc-finger double domain 373-395 Zinc finger, C2H2 type 373-384 C2H2-type zinc finger 373-395 C2H2-type zinc finger 389-411 Zinc-finger double domain 401-423 C2H2-type zinc finger 402-423 Zinc finger, C2H2 type 403-423 C2H2-type zinc finger 416-440 Zinc-finger double domain 429-451 C2H2-type zinc finger 430-451 Zinc finger, C2H2 type 431-449 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MAAPLEAQDQAPGEGEGLLIVKVEDSSWEQESAQHEDGRDSEACRQRFRQFCYGDVHGPH 60 61 EAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQGWVREQHPGSGEEAVALV 120 121 EDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPTVGARRRPSVPQEQHSHSAQPPAL 180 181 LKEGRPGETTDTCFVSGVHGPVALGDIPFYFSREEWGTLDPAQRDLFWDIKRENSRNTTL 240 241 GFGLKGQSEKSLLQEMVPVVPGQTGSDVTVSWSPEEAEAWESENRPRAALGPVVGARRGR 300 301 PPTRRRQFRDLAAEKPHSCGQCGKRFRWGSDLARHQRTHTGEKPHKCPECDKSFRSSSDL 360 361 VRHQGVHTGEKPFSCSECGKSFSRSAYLADHQRIHTGEKPFGCSDCGKSFSLRSYLLDHR 420 421 RVHTGERPFGCGECDKSFKQRAHLIAHQSLHAKMAQPVG |
| Interface Residues: | 300, 302, 303, 306, 327, 328, 329, 330, 331, 333, 334, 335, 336, 337, 340, 355, 356, 357, 358, 359, 360, 361, 362, 363, 366, 383, 384, 385, 386, 387, 388, 389, 390, 393, 411, 412, 413, 414, 415, 417, 418, 439, 440, 441, 442, 443, 445, 446 |
| 3D-footprint Homologues: | 5v3j_F, 8ssu_A, 7w1m_H, 6u9q_A, 5kkq_D, 1tf6_A, 5ei9_F, 2kmk_A, 8ssq_A, 6blw_A, 5k5l_F, 4m9v_C, 6e94_A, 7ysf_A, 2jpa_A, 7n5w_A, 5yel_A, 4x9j_A, 2gli_A, 1f2i_J, 8gn3_A, 1g2f_F, 5k5i_A, 6ml4_A, 2drp_D, 8h9h_G, 7y3m_I, 2lt7_A, 1ubd_C, 1tf3_A, 8cuc_F, 7y3l_A, 6jnm_A, 5yj3_D, 5kl3_A, 7txc_E, 1llm_D, 6a57_A, 3uk3_C, 2wbs_A |
| Binding Motifs: | UN0601.1 mGAmmkCrGGCGGCG MA2121.1 gCCCAGGCwGsr |
| Binding Sites: | MA2121.1.1 MA2121.1.10 MA2121.1.11 MA2121.1.12 MA2121.1.13 / MA2121.1.16 / MA2121.1.17 / MA2121.1.18 MA2121.1.14 MA2121.1.15 MA2121.1.19 MA2121.1.2 MA2121.1.20 MA2121.1.3 MA2121.1.4 MA2121.1.5 MA2121.1.6 MA2121.1.7 MA2121.1.8 MA2121.1.9 |
| Publications: | Schmitges FW, Radovani E, Najafabadi HS, Barazandeh M, Campitelli LF, Yin Y, Jolma A, Zhong G, Guo H, Kanagalingam T, Dai WF, Taipale J, Emili A, Greenblatt JF, Hughes TR. Multiparameter functional diversity of human C2H2 zinc finger proteins. Genome Res 26:1742-1752 (2016). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.