Transcription Factor
| Accessions: | IRF5 (HT-SELEX2 May2017) |
| Names: | ENSG00000128604, IRF5 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: IRF experiment: HT-SELEX Hamming distance: 1 cycle: 2, TF family: IRF experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: IRF experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 2, TF family: IRF experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3 |
| Length: | 139 |
| Pfam Domains: | 13-121 Interferon regulatory factor transcription factor |
| Sequence: (in bold interface residues) | 1 NQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDN 60 61 TIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVC 120 121 SNGPAPTDSQPPEDYSFGA |
| Interface Residues: | 48, 50, 83, 87, 88, 90, 91, 94, 95 |
| 3D-footprint Homologues: | 2pi0_B, 1if1_B, 2o61_A, 2irf_L, 7oot_B |
| Binding Motifs: | IRF5_2 cCGAAACCGAaACy IRF5_4 cCGAAACCGAAACy IRF5_methyl_1 vyGAAACcGAwACy IRF5_methyl_3 syGAAACCGAAACy |
| Related annotations: | PaperBLAST |
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