Transcription Factor

Accessions: Q8IZC7 (JASPAR 2024)
Names: Zinc finger protein 101, Zinc finger protein HZF12, ZN101_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q8IZC7
Length: 436
Pfam Domains: 4-44 KRAB box
94-112 Zinc-finger double domain
103-124 Zinc finger, C2H2 type
103-124 C2H2-type zinc finger
103-114 C2H2-type zinc finger
164-179 Zinc-finger double domain
168-191 C2H2-type zinc finger
169-191 Zinc finger, C2H2 type
169-191 C2H2-type zinc finger
212-232 Zinc-finger double domain
225-247 Zinc finger, C2H2 type
241-262 Zinc-finger double domain
252-262 C2H2-type zinc finger
253-276 C2H2-type zinc finger
253-276 Zinc finger, C2H2 type
282-304 C2H2-type zinc finger
299-320 Zinc-finger double domain
309-330 C2H2-type zinc finger
310-332 C2H2-type zinc finger
324-349 Zinc-finger double domain
337-361 C2H2-type zinc finger
338-360 Zinc finger, C2H2 type
338-360 C2H2-type zinc finger
353-375 Zinc-finger double domain
365-376 C2H2-type zinc finger
366-388 Zinc finger, C2H2 type
366-388 C2H2-type zinc finger
380-404 Zinc-finger double domain
394-416 Zinc finger, C2H2 type
394-416 C2H2-type zinc finger
395-404 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MDSVAFEDVAVNFTQEEWALLSPSQKNLYRDVTLETFRNLASVGIQWKDQDIENLYQNLG 60
61 IKLRSLVERLCGRKEGNEHRETFSQIPDCHLNKKSQTGVKPCKCSVCGKVFLRHSFLDRH 120
121 MRAHAGHKRSECGGEWRETPRKQKQHGKASISPSSGARRTVTPTRKRPYECKVCGKAFNS 180
181 PNLFQIHQRTHTGKRSYKCREIVRAFTVSSFFRKHGKMHTGEKRYECKYCGKPIDYPSLF 240
241 QIHVRTHTGEKPYKCKQCGKAFISAGYLRTHEIRSHALEKSHQCQECGKKLSCSSSLHRH 300
301 ERTHSGGKLYECQKCAKVFRCPTSLQAHERAHTGERPYECNKCGKTFNYPSCFRRHKKTH 360
361 SGEKPYECTRCGKAFGWCSSLRRHEMTHTGEKPFDCKQCGKVFTFSNYLRLHERTHLAGR 420
421 SQCFGRRQGDHLSPGV
Interface Residues: 132, 133, 154, 158, 179, 180, 183, 186, 208, 209, 210, 211, 214, 218, 235, 236, 237, 238, 239, 242, 264, 265, 266, 267, 269, 270, 292, 293, 294, 295, 296, 298, 299, 303, 310, 320, 321, 322, 323, 324, 326, 327, 329, 330, 333, 348, 349, 350, 351, 352, 354, 355, 356, 361, 375, 376, 377, 378, 379, 380, 381, 382, 383, 384, 387, 404, 405, 406, 407, 408, 411
3D-footprint Homologues: 3s57_A, 7w1m_H, 8ssq_A, 8ssu_A, 5v3j_F, 2gli_A, 3uk3_C, 1tf6_A, 7y3m_I, 2i13_A, 7ysf_A, 5yel_A, 6jnm_A, 6wmi_A, 2lt7_A, 6a57_A, 2kmk_A, 7n5w_A, 5kkq_D, 6u9q_A, 5ei9_F, 6ml4_A, 8h9h_G, 7eyi_G, 6e94_A, 2jpa_A, 1ubd_C, 1tf3_A, 6blw_A, 4x9j_A, 1mey_C, 5kl3_A, 5und_A, 1g2f_F, 5k5i_A, 4m9v_C, 8cuc_F, 7y3l_A, 8gn3_A, 1llm_D, 2wbs_A, 7txc_E, 2drp_D, 1f2i_J, 5yj3_D
Binding Motifs: UN0160.1 ayACwGGGGCma
UN0160.2 ACwGGGGC
Binding Sites: UN0160.2.12
UN0160.2.4
UN0160.1.1 / UN0160.1.2 / UN0160.1.3
UN0160.1.10 / UN0160.1.5
UN0160.1.11 / UN0160.1.6
UN0160.1.12 / UN0160.1.7
UN0160.1.13
UN0160.1.14
UN0160.1.15 / UN0160.1.8
UN0160.1.16
UN0160.1.17 / UN0160.1.9
UN0160.1.10 / UN0160.1.18
UN0160.1.11 / UN0160.1.19
UN0160.1.13 / UN0160.1.20
UN0160.1.1 / UN0160.1.2 / UN0160.1.4 / UN0160.1.6
UN0160.1.5
UN0160.1.7
UN0160.1.3 / UN0160.1.8
UN0160.1.4 / UN0160.1.9
UN0160.1.12
UN0160.1.14
UN0160.1.15
UN0160.1.16
UN0160.1.17
UN0160.1.18
UN0160.1.19
UN0160.1.20
UN0160.2.1 / UN0160.2.19 / UN0160.2.2
UN0160.2.10 / UN0160.2.11 / UN0160.2.13 / UN0160.2.14 / UN0160.2.15 / UN0160.2.18 / UN0160.2.20 / UN0160.2.7 / UN0160.2.8
UN0160.2.16
UN0160.2.17 / UN0160.2.5 / UN0160.2.9
UN0160.2.3
UN0160.2.6
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.