Transcription Factor

Accessions: 1hbx_G (3D-footprint 20231221)
Names: ELK4_HUMAN, ETS domain-containing protein Elk-4, ETS-DOMAIN PROTEIN ELK-4, SAP-1, Serum response factor accessory protein 1, SRF accessory protein 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P28324
Length: 112
Pfam Domains: 4-85 Ets-domain
Sequence:
(in bold interface residues)
1 DSAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLSR 60
61 ALRYYYVKNIIKKVNGQKFVYKFVSYPEILNMSRNDYIHSGLYSSFTLNSLN
Interface Residues: 56, 57, 59, 60, 61, 63, 64, 78
3D-footprint Homologues: 4uno_A, 3jtg_A, 1dux_F, 7jsa_J, 3zp5_A, 8ee9_F, 4mhg_A, 2stt_A, 4iri_A, 1bc8_C, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A
Binding Motifs: 1hbx_G ttCCG
1hbx_ABG CGGAAnTCCTAATTAG
Binding Sites: 1hbx_C
1hbx_W
Publications: Hassler M., Richmond T. J. The B-box dominates SAP-1-SRF interactions in the structure of the ternary complex.. EMBO J. 20:3018-3028 (2001). [Pubmed]
Related annotations: PaperBLAST

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