Transcription Factor
| Accessions: | GLI3_MOUSE (HOCOMOCO 10) |
| Names: | GLI3 C-terminally truncated form, GLI3 form of 190 kDa, GLI3 form of 83 kDa, GLI3 full length protein, GLI3_MOUSE, GLI3-190, GLI3-83, GLI3FL, Transcriptional activator GLI3 |
| Organisms: | Mus musculus |
| Libraries: | HOCOMOCO 10 1 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] |
| Uniprot: | Q61602 |
| Length: | 1583 |
| Pfam Domains: | 513-540 Zinc finger, C2H2 type 533-558 Zinc-finger double domain 546-570 Zinc finger, C2H2 type 546-570 C2H2-type zinc finger 562-589 Zinc-finger double domain 576-601 Zinc finger, C2H2 type 576-601 C2H2-type zinc finger 607-632 C2H2-type zinc finger 607-632 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MEAQAHSSTATERKKAENSIGKCPTRTDVSEKAVASSTTSNEDESPGQIYHRERRNAITM 60 61 QPQSVQGLNKISEEPSTSSDERASLIKKEIHGSLPHLAEPSLPYRGTVFAMDPRNGYMEP 120 121 HYHPPHLFPAFHPPVPIDARHHEGRYHYDPSPIPPLHVPSALSSSPTYPDLPFIRISPHR 180 181 NPTAASESPFSPPHPYINPYMDYIRSLHSSPSLSMISAARGLSPTDAPHAGVSPAEYYHQ 240 241 MALLTGQRSPYADILPSAATAGAGAIHMEYLHAMDSTRFPSPRLSARPSRKRTLSISPLS 300 301 DHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHLSASAISPALSFTYPSAPVSLHMH 360 361 QQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSSGPSESSQSKPTSE 420 421 SAVSSTGDPMHNKRSKIKPDEDLPSPGSRGQQEQPEGTTLVKEEADKDESKQEPEVIYET 480 481 NCHWEGCTREFDTQDQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRH 540 541 TGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRT 600 601 HSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDMHPRPPPPRDSGSHS 660 661 QSRSPGRPTQGAFGEQKELSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPI 720 721 SNYSNSGLELPLTDGGSVADLSAIDETPIMDSTISTATTALALQARRNPAGTKWMEHIKL 780 781 ERLKQVNGMFPRLNPILPSKAPAVSPLIGNGTQSNNNYSSGGPGTLLPSRSDLSGVDFTV 840 841 LNTLNRRDSNTSTISSAYLSSRRSSGISPCFSSRRSSEASQAEGRPQNVSVADSYDPIST 900 901 DASRRSSEASQGDGLPSLLSLTPVQQYRLKAKYAAATGGPPPTPLPHMERLSLKTKMALL 960 961 GEGRDSGVTLPPVHPPRRCSDGGGHTYRGRHLMPHDALANSVRRASDPVRTVSENMSLAR 1020 1021 VQRFSSLNSFNPPNLPPSVEKRSLVLQNYTRQESSQPRYFQASPCPPSITENVALEALTM 1080 1081 DADANLNDEDLLPDDVVQYLNSQNQTGYGQQLQSGISEDSKVAHEPEDLDLAGLPDSHVG 1140 1141 QEYPALEQPCSEGSKTDLPIQWNEVSSGTSDLSSSKLKCGQQRPSAQQPRGFGLYNNMVV 1200 1201 HPHNLWKVGTGPAGGYQTLGENSSTYNGPEHFAIHSGDGLGTNGNTFHEQPFKTQQYGSQ 1260 1261 LNRQPLTSSALDHACGTGIQGSKLKGNSLQENGGLLDFSLSVAPNELAGNTVNGMQTQDQ 1320 1321 MGQGYIAHQLLSGSMQHQGPSRPGQQVLGQVGATSHINIYQGTESCLPGTQDNSSQPSSM 1380 1381 AAIRGYQPCASYGGNRRQAMPRGNLTLQQGQLSDMSQSSRVNSIKMEAQGQSQQLCSTVQ 1440 1441 NYSGQFYDQTMGFSQQDRKAGSFSLSDANCLLQGNGTENSELLSPGANQVTSTVDSFESH 1500 1501 DLEGVQIDFDAIIDDGDHTSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPSLSMGTTNM 1560 1561 AIGDMSSLLTSLAEESKFLAVMQ |
| Interface Residues: | 492, 493, 495, 496, 499, 518, 528, 529, 530, 531, 532, 534, 535, 537, 538, 541, 558, 559, 560, 561, 562, 564, 565, 588, 589, 590, 591, 592, 593, 594, 595, 596, 599, 620, 621, 622, 623, 624, 625, 626, 627 |
| 3D-footprint Homologues: | 7w1m_H, 5yel_A, 6wmi_A, 1ubd_C, 2kmk_A, 8cuc_F, 1tf3_A, 7y3l_A, 7n5w_A, 6blw_A, 6jnm_A, 3uk3_C, 5k5i_A, 6ml4_A, 5v3j_F, 2gli_A, 1tf6_A, 5ei9_F, 7eyi_G, 8h9h_G, 2i13_A, 6e94_A, 6a57_A, 2jpa_A, 5kkq_D, 8ssq_A, 8ssu_A, 1f2i_J, 1g2f_F, 6u9q_A, 4x9j_A, 1llm_D, 7txc_E, 5kl3_A, 7ysf_A, 5yj3_D, 1mey_C, 5und_A, 2lt7_A, 7y3m_I, 2drp_D, 2wbs_A, 4m9v_C |
| Binding Motifs: | GLI3_MOUSE.H10MO.B|M01130 bTGGGTGGTcy |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.