Transcription Factor

Accessions: 1qp9_A (3D-footprint 20231221)
Names: CYP1 activatory protein, CYP1(HAP1-PC7) ACTIVATORY PROTEIN, HAP1_YEASX, Heme activator protein 1, Heme-responsive zinc finger transcription factor HAP1
Organisms: Saccharomyces cerevisiae
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P0CS82
Length: 76
Pfam Domains: 9-43 Fungal Zn(2)-Cys(6) binuclear cluster domain
Sequence:
(in bold interface residues)
1 RKRNRIPLGCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAEEAEKELLKDNEL 60
61 KKLRERVKSLEKTLSK
Interface Residues: 16, 17, 18, 19, 21, 22, 25
3D-footprint Homologues: 1hwt_C, 1pyi_A, 6o19_A, 2er8_C, 3coq_A, 6gys_C, 7uik_T, 1zme_D, 1d66_B, 7eyi_G, 8h9h_G, 7n5w_A, 7y3l_A
Binding Motifs: 1qp9_AB CGCnnnTATCGCnnnTAG
Publications: Lukens A.K, King D.A, Marmorstein R. Structure of HAP1-PC7 bound to DNA: implications for DNA recognition and allosteric effects of DNA-binding on transcriptional activation. Nucleic acids research 28:3853-63 (2000). [Pubmed]
Related annotations: PaperBLAST

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