Transcription Factor

Accessions: 2erg_A (3D-footprint 20231221), 2erg_B (3D-footprint 20231221)
Names: LEUR_YEAST, Regulatory protein LEU3
Organisms: Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P08638
Length: 65
Pfam Domains: 2-41 Fungal Zn(2)-Cys(6) binuclear cluster domain
Sequence:
(in bold interface residues)
1 FACVECRQQKSKCDACERAPEPCTKCAKKNVPCILKRDFRRTYKRARNEAIEKRFKELTR 60
61 TLTNL
Interface Residues: 5, 7, 9, 10, 11, 12, 14, 15, 18, 28, 29, 30, 40, 41
3D-footprint Homologues: 1s40_A, 1f5e_P, 1hwt_C, 2er8_C, 6o19_A, 1pyi_A, 1d66_B, 7uik_T, 3coq_A, 1zme_D, 6gys_C, 2r5y_A, 7vyx_B
Binding Motifs: 2erg_A ccGG
2erg_AB CCGgnncCGG
Binding Sites: 2erg_C / 2erg_D
Publications: Fitzgerald M.X, Rojas J.R, Kim J.M, Kohlhaw G.B, Marmorstein R. Structure of a Leu3-DNA complex: recognition of everted CGG half-sites by a Zn2Cys6 binuclear cluster protein. Structure (London, England : 1993) 14:725-35 (2006). [Pubmed]
Related annotations: PaperBLAST

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