Transcription Factor
| Accessions: | Q5JVG2 (JASPAR 2024) |
| Names: | ZN484_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q5JVG2 |
| Length: | 852 |
| Pfam Domains: | 8-48 KRAB box 370-395 Zinc-finger double domain 384-404 C2H2-type zinc finger 384-406 C2H2-type zinc finger 384-406 Zinc finger, C2H2 type 399-421 Zinc-finger double domain 412-434 C2H2-type zinc finger 412-434 Zinc finger, C2H2 type 429-449 Zinc-finger double domain 439-449 C2H2-type zinc finger 440-462 Zinc finger, C2H2 type 458-479 Zinc-finger double domain 468-488 C2H2-type zinc finger 468-490 C2H2-type zinc finger 468-490 Zinc finger, C2H2 type 482-506 Zinc-finger double domain 496-516 C2H2-type zinc finger 496-518 C2H2-type zinc finger 496-518 Zinc finger, C2H2 type 510-534 Zinc-finger double domain 523-534 C2H2-type zinc finger 524-544 Zinc finger, C2H2 type 524-546 C2H2-type zinc finger 539-561 Zinc-finger double domain 552-574 C2H2-type zinc finger 552-574 Zinc finger, C2H2 type 552-561 C2H2-type zinc finger 567-589 Zinc-finger double domain 580-602 C2H2-type zinc finger 580-602 Zinc finger, C2H2 type 597-618 Zinc-finger double domain 607-618 C2H2-type zinc finger 608-630 C2H2-type zinc finger 608-630 Zinc finger, C2H2 type 626-646 Zinc-finger double domain 636-658 C2H2-type zinc finger 636-658 Zinc finger, C2H2 type 636-656 C2H2-type zinc finger 650-675 Zinc-finger double domain 663-674 C2H2-type zinc finger 664-686 C2H2-type zinc finger 664-686 Zinc finger, C2H2 type 682-702 Zinc-finger double domain 692-712 C2H2-type zinc finger 692-714 C2H2-type zinc finger 692-714 Zinc finger, C2H2 type 709-729 Zinc-finger double domain 720-729 C2H2-type zinc finger 720-742 C2H2-type zinc finger 720-742 Zinc finger, C2H2 type 734-757 Zinc-finger double domain 747-757 C2H2-type zinc finger 748-770 Zinc finger, C2H2 type 765-786 Zinc-finger double domain 776-798 Zinc finger, C2H2 type 776-796 C2H2-type zinc finger 776-798 C2H2-type zinc finger 790-807 Zinc-finger double domain |
| Sequence: (in bold interface residues) | 1 MTKSLESVSFKDVTVDFSRDEWQQLDLAQKSLYREVMLENYFNLISVGCQVPKPEVIFSL 60 61 EQEEPCMLDGEIPSQSRPDGDIGFGPLQQRMSEEVSFQSEININLFTRDDPYSILEELWK 120 121 DDEHTRKCGENQNKPLSRVVFINKKTLANDSIFEYKDIGEIVHVNTHLVSSRKRPHNCNS 180 181 CGKNLEPIITLYNRNNATENSDKTIGDGDIFTHLNSHTEVTACECNQCGKPLHHKQALIQ 240 241 QQKIHTRESLYLFSDYVNVFSPKSHAFAHESICAEEKQHECHECEAVFTQKSQLDGSQRV 300 301 YAGICTEYEKDFSLKSNRQKTPYEGNYYKCSDYGRAFIQKSDLFRCQRIHSGEKPYEYSE 360 361 CEKNLPQNSNLNIHKKIHTGGKHFECTECGKAFTRKSTLSMHQKIHTGEKPYVCTECGKA 420 421 FIRKSHFITHERIHTGEKPYECSDCGKSFIKKSQLHVHQRIHTGENPFICSECGKVFTHK 480 481 TNLIIHQKIHTGERPYICTVCGKAFTDRSNLIKHQKIHTGEKPYKCSDCGKSFTWKSRLR 540 541 IHQKCHTGERHYECSECGKAFIQKSTLSMHQRIHRGEKPYVCTECGKAFFHKSHFITHER 600 601 IHTGEKPYECSICGKSFTKKSQLHVHQQIHTGEKPYRCAECGKAFTDRSNLFTHQKIHTG 660 661 EKPYKCSDCGKAFTRKSGLHIHQQSHTGERHYECSECGKAFARKSTLIMHQRIHTGEKPY 720 721 ICNECGKSFIQKSHLNRHRRIHTGEKPYECSDCGKSFIKKSQLHEHHRIHTGEKPYICAE 780 781 CGKAFTIRSNLIKHQKIHTKQKPYKCSDLGKALNWKPQLSMPQKSDNGEVECSMPQLWCG 840 841 DSEGDQGQLSSI |
| Interface Residues: | 395, 397, 398, 423, 425, 426, 428, 429, 431, 432, 435, 450, 451, 453, 454, 457, 460, 478, 479, 480, 481, 482, 484, 485, 506, 507, 508, 509, 510, 512, 513, 534, 535, 536, 537, 538, 540, 541, 563, 564, 565, 566, 569, 573, 590, 591, 592, 593, 594, 597, 601, 618, 619, 620, 621, 622, 625, 647, 648, 649, 650, 652, 653, 675, 676, 677, 678, 679, 681, 682, 692, 703, 704, 705, 706, 709, 715, 729, 730, 731, 732, 733, 734, 737, 738, 741, 758, 759, 760, 761, 762, 763, 764, 765, 766, 786, 787, 788, 789, 790, 792, 793 |
| 3D-footprint Homologues: | 1tf6_A, 6blw_A, 5ei9_F, 6wmi_A, 2jpa_A, 1tf3_A, 8cuc_F, 7y3l_A, 5und_A, 2gli_A, 6ml4_A, 6u9q_A, 2drp_D, 5k5l_F, 8gn3_A, 7y3m_I, 5k5i_A, 7w1m_H, 5v3j_F, 2lt7_A, 8ssq_A, 8ssu_A, 2i13_A, 7n5w_A, 5kkq_D, 1llm_D, 8h9h_G, 7eyi_G, 3uk3_C, 6e94_A, 5yj3_D, 5yel_A, 1mey_C, 2kmk_A, 7ysf_A, 1ubd_C, 6jnm_A, 7txc_E, 5kl3_A, 1f2i_J, 1g2f_F, 4x9j_A, 4m9v_C, 6a57_A, 2wbs_A |
| Binding Motifs: | UN0619.1 arrGGAyAGAGGAACAwG |
| Binding Sites: | UN0619.1.1 UN0619.1.10 / UN0619.1.14 UN0619.1.11 / UN0619.1.16 UN0619.1.12 / UN0619.1.18 UN0619.1.13 / UN0619.1.20 UN0619.1.14 UN0619.1.15 UN0619.1.16 UN0619.1.17 UN0619.1.18 UN0619.1.19 UN0619.1.2 UN0619.1.20 UN0619.1.3 / UN0619.1.4 UN0619.1.4 / UN0619.1.6 UN0619.1.5 / UN0619.1.8 UN0619.1.6 / UN0619.1.9 UN0619.1.10 / UN0619.1.7 UN0619.1.11 / UN0619.1.8 UN0619.1.13 / UN0619.1.9 UN0619.1.12 UN0619.1.15 UN0619.1.17 UN0619.1.19 UN0619.1.3 UN0619.1.5 UN0619.1.7 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.