Transcription Factor

Accessions: MBD2_MOUSE (HOCOMOCO 10)
Names: MBD2_MOUSE, Methyl-CpG-binding domain protein 2, Methyl-CpG-binding protein MBD2
Organisms: Mus musculus
Libraries: HOCOMOCO 10 1
1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
Uniprot: Q9Z2E1
Length: 414
Pfam Domains: 150-218 Methyl-CpG binding domain
298-390 C-terminal domain of methyl-CpG binding protein 2 and 3
Sequence:
(in bold interface residues)
1 MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG 60
61 RGRWKQAARGGGVCGRGRGRGRGRGRGRGRGRGRGRPQSGGSGLGGDGGGGAGGCGGGSG 120
121 GGVAPRRDPVPFPSGSSGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDV 180
181 YYFSPSGKKFRSKPQLARYLGNAVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKGKP 240
241 DLNTTLPIRQTASIFKQPVTKFTNHPSNKVKSDPQRMNEQPRQLFWEKRLQGLSASDVTE 300
301 QIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQVSAAVEKNPAVWLNTSQP 360
361 LCKAFIVTDEDIRKQEERVQQVRKKLEEALMADILSRAADTEEVDIDMDSGDEA
Interface Residues: 169, 173, 174, 177, 179, 181, 189, 191
3D-footprint Homologues: 6ceu_B, 2moe_A, 6ogk_A, 3vxv_A, 6c1t_D, 2ky8_A
Binding Motifs: MBD2_MOUSE.H10MO.B|M01202 ssSkCCGGmgr
Related annotations: PaperBLAST

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