Transcription Factor
| Accessions: | O08674 (JASPAR 2024) |
| Names: | RBPJL_MOUSE, Recombining binding protein suppressor of hairless-like protein, Transcription factor RBP-L |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | O08674 |
| Length: | 515 |
| Pfam Domains: | 66-204 LAG1, DNA binding 205-357 Beta-trefoil DNA-binding domain 388-473 IPT/TIG domain |
| Sequence: (in bold interface residues) | 1 MDPRETTDPSLPPGPLTHLSLPDSSEVRLQSDGPSLLGSWTRSPPEHAIILREGVRTCLQ 60 61 QRCEQTVWILHAKVAQKSYGNEKRFFCPPPCVYLAGPGWRVKPMQDQALQSAETGPTVCG 120 121 YMGLDGASGSAPETQKLNFEEQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGQELG 180 181 TFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASA 240 241 RQWAAFTLHLADGHCSQGDFPPQEGYIRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLD 300 301 VDEPISQLHKCAFQFPSDTPGGAGTYLCLATEKVVRFQASLCPKEANRALLNDSSCWTII 360 361 GTESVEFTFSTSLACTREPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEA 420 421 ETMYRSPRSLVCVVPDVAAFGSDWRWLRTPITVPVSLLRADALFYPSPFSFTYTPEYSAL 480 481 PRLPNAQEPAPDADTLLESIHHEFTRTNFHLFCPT |
| Interface Residues: | 79, 82, 84, 191, 192, 221, 222 |
| 3D-footprint Homologues: | 3iag_C |
| Binding Motifs: | MA1621.1 svmaCACCTGtsyc |
| Binding Sites: | MA1621.1.1 MA1621.1.10 / MA1621.1.6 MA1621.1.11 MA1621.1.12 MA1621.1.13 MA1621.1.14 MA1621.1.15 / MA1621.1.7 MA1621.1.16 / MA1621.1.8 MA1621.1.17 MA1621.1.18 MA1621.1.19 MA1621.1.1 / MA1621.1.2 / MA1621.1.3 / MA1621.1.4 / MA1621.1.6 / MA1621.1.8 MA1621.1.20 / MA1621.1.9 MA1621.1.3 / MA1621.1.7 MA1621.1.2 / MA1621.1.4 MA1621.1.5 MA1621.1.5 / MA1621.1.9 MA1621.1.10 MA1621.1.11 MA1621.1.12 MA1621.1.13 MA1621.1.14 MA1621.1.15 MA1621.1.16 MA1621.1.17 MA1621.1.18 MA1621.1.19 MA1621.1.20 |
| Publications: | Masui T, Swift GH, Deering T, Shen C, Coats WS, Long Q, Elsässer HP, Magnuson MA, MacDonald RJ. Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells. Gastroenterology 139:270-80 (2010). [Pubmed] |
| Related annotations: | PaperBLAST |
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