Transcription Factor

						

			
Accessions: 5zx2_F (3D-footprint 20231221)

			
Names: Alternative RNA polymerase sigma factor SigH, ECF RNA polymerase sigma factor SigH, ECF sigma factor SigH, RNA polymerase sigma-H factor, SIGH_MYCTU
Organisms: Mycobacterium tuberculosis, strain ATCC 25618 / H37Rv
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P9WGH9
Length: 175
Pfam Domains:     16-78 Sigma-70 region 2 
  119-170 Sigma-70, region 4
  123-171 Sigma-70, region 4
Sequence: 
(in bold interface residues)		   1 DEELTARFERDAIPLLDQLYGGALRMTRNPADAEDLLQETMVKAYAGFRSFRHGTNLKAW   60
  61 LYRILTNTYINSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALPDTEI  120
 121 KEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQLRGLLA
Interface Residues: 43, 47, 51, 52, 54, 55, 58, 59, 60, 62, 63, 64, 67, 71, 93, 94, 145, 158, 160, 161, 164, 165
3D-footprint Homologues: 4lup_A, 3g00_B, 6jhe_A, 2h27_A
Binding Motifs: 5zx2_F GGGTnTACcACnnnnnnnnnnnnnnnGTnCC
Binding Sites: 5zx2_G
5zx2_H
			
Publications: Li L, Fang C, Zhuang N, Wang T, Zhang Y. Structural basis for transcription initiation by bacterial ECF σ factors. Nat Commun 10:1153 (2019). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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