Transcription Factor

						

			
Accessions: 6fqq_A (3D-footprint 20231221)

			
Names: 5'-TG-3'-interacting factor 1, Homeobox protein TGIF1, TGIF1_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q15583
Length: 60
Pfam Domains:     13-52 Homeobox KN domain
    15-52 Homeobox domain
Sequence: 
(in bold interface residues)		   1 NLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRK   60
Interface Residues: 43, 44, 47, 48, 49, 51, 52
3D-footprint Homologues: 4j19_B, 1le8_A, 5zjt_E, 2d5v_B, 1fjl_B, 1mnm_C, 6fqp_B, 2hdd_A, 1k61_B, 4xrm_B, 1puf_B, 6fqq_E, 4xrs_G, 1zq3_P, 1du0_A, 7psx_B, 3a01_E, 1le8_B, 2hos_A
Binding Motifs: 6fqq_AB tGACAgnTGTCA
			
Publications: Guca E, Suñol D, Ruiz L, Konkol A, Cordero J, Torner C, Aragon E, Martin-Malpartida P, Riera A, Macias MJ. TGIF1 homeodomain interacts with Smad MH1 domain and represses TGF-β signaling. Nucleic Acids Res 46:9220-9235 (2018). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.