Transcription Factor

						

			
Accessions: 6t78_A (3D-footprint 20231221)

			
Names: SOX11_HUMAN, Transcription factor SOX-11
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P35716
Length: 77
Pfam Domains:      4-72 HMG (high mobility group) box
     5-62 Domain of unknown function (DUF1898)
Sequence: 
(in bold interface residues)		   1 SGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERL   60
  61 RLKHMADYPDYKYRPRK
Interface Residues: 6, 9, 11, 12, 13, 15, 19, 30, 31, 32, 35, 73, 77
3D-footprint Homologues: 4s2q_D, 1qrv_A, 3tmm_A, 4y60_C, 2gzk_A, 1j5n_A, 6jrp_D, 2lef_A, 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 1hry_A, 3tq6_B, 1ckt_A
Binding Motifs: 6t78_A TaAATTgT
6t78_AB ACAATAAATTGT
Binding Sites: 6t78_C
6t78_D
			
Publications: Dodonova SO, Zhu F, Dienemann C, Taipale J, Cramer P. Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature 580:669-672 (2020). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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