Transcription Factor
| Accessions: | NKX31_HUMAN (HOCOMOCO 10), Q99801 (JASPAR 2024) |
| Names: | Homeobox protein NK-3 homolog A, Homeobox protein Nkx-3.1, NKX31_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q99801 |
| Length: | 234 |
| Pfam Domains: | 125-181 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MLRVPEPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEP 60 61 EPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTP 120 121 KQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTK 180 181 RKQLSSELGDLEKHSSLPALKEEAFSRASLVSVYNSYPYYPYLYCVGSWSPAFW |
| Interface Residues: | 104, 108, 124, 125, 126, 127, 128, 166, 167, 169, 170, 173, 174, 177, 178, 181 |
| 3D-footprint Homologues: | 1e3o_C, 1au7_A, 3d1n_M, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1nk2_P, 1fjl_B, 5zfz_A, 1zq3_P, 1jgg_B, 3lnq_A, 2lkx_A, 7q3o_C, 2ld5_A, 7psx_B, 1b72_A, 5flv_I, 2hos_A, 1ig7_A, 5zjt_E, 4cyc_A, 5hod_A, 3l1p_A, 3a01_E, 5jlw_D, 6es3_K, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 1le8_A, 2xsd_C, 2h8r_B, 7xrc_C, 1o4x_A, 1le8_B, 1du0_A, 4qtr_D, 1mnm_C, 1puf_B, 1k61_B, 8g87_X |
| Binding Motifs: | NKX31_HUMAN.H10MO.C|M01377 wwTAAGTAtwtww MA0124.1 aTACTTA |
| Binding Sites: | MA0124.1.1 MA0124.1.10 MA0124.1.11 MA0124.1.12 MA0124.1.13 MA0124.1.14 MA0124.1.15 MA0124.1.16 MA0124.1.17 MA0124.1.18 MA0124.1.19 MA0124.1.2 MA0124.1.20 MA0124.1.3 MA0124.1.4 MA0124.1.5 MA0124.1.6 MA0124.1.7 MA0124.1.8 MA0124.1.9 |
| Publications: | Steadman D. J., Giuffrida D., Gelmann E. P. DNA-binding sequence of the human prostate-specific homeodomain protein NKX3.1. Nucleic Acids Res. 28:2389-2395 (2000). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.