Transcription Factor
| Accessions: | P51508 (JASPAR 2024) |
| Names: | HFZ20, Zinc finger protein 81, ZNF81_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P51508 |
| Length: | 661 |
| Pfam Domains: | 21-61 KRAB box 319-339 Zinc-finger double domain 329-342 C2H2-type zinc finger 330-352 Zinc finger, C2H2 type 330-352 C2H2-type zinc finger 347-367 Zinc-finger double domain 357-374 C2H2-type zinc finger 358-380 Zinc finger, C2H2 type 358-380 C2H2-type zinc finger 372-396 Zinc-finger double domain 385-396 C2H2-type zinc finger 386-408 C2H2-type zinc finger 386-408 Zinc finger, C2H2 type 400-425 Zinc-finger double domain 414-436 Zinc finger, C2H2 type 414-436 C2H2-type zinc finger 414-434 C2H2-type zinc finger 429-451 Zinc-finger double domain 442-464 Zinc finger, C2H2 type 442-464 C2H2-type zinc finger 442-451 C2H2-type zinc finger 457-479 Zinc-finger double domain 469-490 C2H2-type zinc finger 470-492 Zinc finger, C2H2 type 470-492 C2H2-type zinc finger 485-509 Zinc-finger double domain 498-520 C2H2-type zinc finger 498-520 Zinc finger, C2H2 type 498-520 C2H2-type zinc finger 512-536 Zinc-finger double domain 526-545 C2H2-type zinc finger 526-548 Zinc finger, C2H2 type 526-548 C2H2-type zinc finger 540-563 Zinc-finger double domain 554-576 Zinc finger, C2H2 type 554-576 C2H2-type zinc finger 571-592 Zinc-finger double domain 581-592 C2H2-type zinc finger 582-604 Zinc finger, C2H2 type 582-604 C2H2-type zinc finger 596-620 Zinc-finger double domain 610-632 C2H2-type zinc finger 610-629 C2H2-type zinc finger 610-632 Zinc finger, C2H2 type 624-649 Zinc-finger double domain 637-648 C2H2-type zinc finger 638-660 Zinc finger, C2H2 type 638-658 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MPANEDAPQPGEHGSACEVSVSFEDVTVDFSREEWQQLDSTQRRLYQDVMLENYSHLLSV 60 61 GFEVPKPEVIFKLEQGEGPWTLEGEAPHQSCSDGKFGIKPSQRRISGKSTFHSEMEGEDT 120 121 RDDSLYSILEELWQDAEQIKRCQEKHNKLLSRTTFLNKKILNTEWDYEYKDFGKFVHPSP 180 181 NLILSQKRPHKRDSFGKSFKHNLDLHIHNKSNAAKNLDKTIGHGQVFTQNSSYSHHENTH 240 241 TGVKFCERNQCGKVLSLKHSLSQNVKFPIGEKANTCTEFGKIFTQRSHFFAPQKIHTVEK 300 301 PHELSKCVNVFTQKPLLSIYLRVHRDEKLYICTKCGKAFIQNSELIMHEKTHTREKPYKC 360 361 NECGKSFFQVSSLLRHQTTHTGEKLFECSECGKGFSLNSALNIHQKIHTGERHHKCSECG 420 421 KAFTQKSTLRMHQRIHTGERSYICTQCGQAFIQKAHLIAHQRIHTGEKPYECSDCGKSFP 480 481 SKSQLQMHKRIHTGEKPYICTECGKAFTNRSNLNTHQKSHTGEKSYICAECGKAFTDRSN 540 541 FNKHQTIHTGEKPYVCADCGRAFIQKSELITHQRIHTTEKPYKCPDCEKSFSKKPHLKVH 600 601 QRIHTGEKPYICAECGKAFTDRSNFNKHQTIHTGDKPYKCSDCGKGFTQKSVLSMHRNIH 660 661 T |
| Interface Residues: | 341, 343, 344, 347, 369, 370, 371, 372, 375, 396, 397, 399, 400, 403, 425, 426, 427, 428, 430, 431, 435, 442, 452, 453, 454, 455, 456, 458, 459, 480, 481, 482, 483, 484, 485, 487, 508, 509, 510, 511, 512, 515, 516, 519, 536, 537, 538, 539, 540, 541, 542, 543, 544, 547, 564, 565, 566, 567, 568, 570, 571, 573, 574, 575, 577, 591, 593, 594, 595, 596, 599, 603, 620, 621, 622, 623, 624, 626, 627, 648, 649, 650, 651, 652, 655 |
| 3D-footprint Homologues: | 6u9q_A, 7w1m_H, 5yel_A, 3uk3_C, 8ssq_A, 8ssu_A, 2kmk_A, 7n5w_A, 5v3j_F, 6blw_A, 8h9h_G, 2lt7_A, 1tf3_A, 8cuc_F, 7y3l_A, 5k5i_A, 6ml4_A, 5k5l_F, 2gli_A, 2wbs_A, 1tf6_A, 5ei9_F, 6e94_A, 7y3m_I, 7txc_E, 5yj3_D, 4m9v_C, 7ysf_A, 1ubd_C, 6jnm_A, 4x9j_A, 1f2i_J, 5kkq_D, 6a57_A, 2jpa_A, 5kl3_A, 1llm_D, 8gn3_A, 1g2f_F, 2drp_D |
| Binding Motifs: | UN0235.1 mTrGTACAACCACTwTGGAAAACA |
| Binding Sites: | UN0235.1.1 UN0235.1.10 UN0235.1.11 UN0235.1.12 UN0235.1.13 UN0235.1.14 UN0235.1.15 UN0235.1.16 UN0235.1.17 UN0235.1.18 UN0235.1.18 / UN0235.1.19 UN0235.1.2 UN0235.1.19 / UN0235.1.20 UN0235.1.3 UN0235.1.4 UN0235.1.5 UN0235.1.6 UN0235.1.7 UN0235.1.8 UN0235.1.9 UN0235.1.20 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.