Transcription Factor
Accessions: | 1je8_E (3D-footprint 20231221), 1zg5_E (3D-footprint 20231221) |
Names: | NARL_ECOLI, Nitrate/Nitrite Response Regulator Protein NARL |
Organisms: | Escherichia coli, strain K12 |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P0AF28 |
Length: | 67 |
Pfam Domains: | 5-60 Bacterial regulatory proteins, luxR family 5-50 Sigma-70, region 4 5-49 Sigma-70, region 4 9-48 Winged helix-turn-helix DNA-binding |
Sequence: (in bold interface residues) | 1 ERDVNQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVW 60 61 VHQERIF |
Interface Residues: | 34, 35, 36, 37, 39, 40, 41, 42, 43, 48, 49, 51, 52, 53 |
3D-footprint Homologues: | 4m6f_A, 7ve5_B, 5w43_B, 8dq1_C, 4wuh_B, 1je8_F, 1zlk_A |
Binding Motifs: | 1je8_EF TaCCnAnnnnTnGGtA 1zg5_E ThCCmC 1zg5_EF TACCCCtnnAGGGGTA |
Binding Sites: | 1zg5_G / 1zg5_H |
Publications: | Maris AE., Sawaya MR., Kaczor-Grzeskowiak M., Jarvis MR., Bearson SM., Kopka ML., Schroder I., Gunsalus RP., Dickerson RE. Dimerization allows DNA target site recognition by the NarL response regulator. Nat Struct Biol. 9(10):771-8 (2002). [Pubmed] Maris AE., Kaczor-Grzeskowiak M., Ma Z., Kopka ML., Gunsalus RP., Dickerson RE. Primary and secondary modes of DNA recognition by the NarL two-component response regulator. Biochemistry. 44(44):14538-52 (2005). [Pubmed] |
Related annotations: | PaperBLAST |
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