Transcription Factor

						

			
Accessions: MIXL1_full (HumanTF 1.0)

			
Names: hMix, Homeobox protein MIXL1, Homeodomain protein MIX, Mix.1 homeobox-like protein, MIX1 homeobox-like protein 1, MIXL1, MIXL1_HUMAN
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q9H2W2
Notes: Ensembl ID: ENSG00000185155; Full protein sequence; TF family: homeodomain; Clone source: hORFeome
Length: 233
Pfam Domains:    87-143 Homeobox domain
Sequence: 
(in bold interface residues)		   1 MATAESRALQFAEGAAFPAYRAPHAGGALLPPPSPAAALLPAPPAGPGPATFAGFLGRDP   60
  61 GPAPPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLA  120
 121 ALTLLPESRIQVWFQNRRAKSRRQSGKSFQPLARPEIILNHCAPGTETKCLKPQLPLEVD  180
 181 VNCLPEPNGVGGGISDSSSQGQNFETCSPLSEDIGSKLDSWEEHIFSAFGNF*
Interface Residues: 86, 87, 88, 89, 90, 128, 129, 131, 132, 135, 136, 138, 139, 140, 142, 143
3D-footprint Homologues: 4j19_B, 3cmy_A, 1ig7_A, 5zfz_A, 1puf_A, 3d1n_M, 8ejp_B, 6a8r_A, 8pmf_A, 1fjl_B, 1nk2_P, 1jgg_B, 3lnq_A, 1zq3_P, 2lkx_A, 6es3_K, 7q3o_C, 2ld5_A, 8eml_B, 1b72_A, 4xrs_G, 2hdd_A, 9b8u_A, 4cyc_A, 2r5y_A, 8ik5_C, 5flv_I, 2hos_A, 5zjt_E, 1puf_B, 8osb_E, 5hod_A, 3a01_E, 7psx_B, 5jlw_D, 3rkq_B, 7xrc_C, 2xsd_C, 1e3o_C, 1le8_A, 1du0_A, 6wig_A, 4qtr_D, 6m3d_C
Binding Motifs: MIXL1_full wyyAATTArm
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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