Transcription Factor

Accessions: T081972_1.02 (CISBP 1.02), FOXJ2_MOUSE (HOCOMOCO 10), Q9ES18 (JASPAR 2024)
Names: Foxj2, T081972_1.02;, Fork head homologous X, Forkhead box protein J2, FOXJ2_MOUSE
Organisms: Mus musculus
Libraries: CISBP 1.02 1, HOCOMOCO 10 2, JASPAR 2024 3
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:PBM, family:Forkhead
Length: 565
Pfam Domains: 66-144 Fork head domain
Sequence:
(in bold interface residues)
1 MASDLESSLTSIDWLPQLTLRATIEKLGSASQAGPPGGARKCSPGSPTDPNATLSKDEAA 60
61 VHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSL 120
121 NKCFRKVPRPRDDPGKGSYWTIDTCPDISRKRRHPPDDDLSQDSPEQEASKSPRGGVPGS 180
181 GEASLSHEGTPQMSLQSPSSVANYSQGPGSVDGGAVAAGAPGQESTEGAPPLYNTNHDFK 240
241 FSYSEINFQDLSWSFRNLYKSMLERSSSSQHGFSSLLGDMPPSNNYYVYQQQQQQQPPPQ 300
301 PQPPPQQPQPQQQQAPTQGPSNVGGAPPLHTPSPDGCTTPGGKQAGAEGYGPPTGMAMHP 360
361 PPLQHGGYHPHQHHPHSHPAQQPPQPQAQSQASINSTGFAFPPDWCSNIDSLKESFKMVN 420
421 RLNWSSIEQSQFSELMESLRQAEQRNWTLDQHHIANLCDSLNHFLTQTGHMPQQGGSHRP 480
481 PAPSRITDSCALTSGKPEPSMNQVNSYGHPQASHLYPGPAPMYPISTQDSAGYNRPAHHM 540
541 VPRPPVPPPGANEEITDDFDWDLIT
Interface Residues: 109, 111, 112, 113, 115, 116, 117, 119, 120, 129, 136
3D-footprint Homologues: 7vox_H, 2hdc_A, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 3l2c_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 3qrf_G
Binding Motifs: M0721_1.02 rtmAAyAaw
M0722_1.02 rTAAACAa
MA0614.1 rTAAACAa
FOXJ2_MOUSE.H10MO.C|M01104 TrTTTrTtTw
Publications: Filant J, Lydon JP, Spencer TE. Integrated chromatin immunoprecipitation sequencing and microarray analysis identifies FOXA2 target genes in the glands of the mouse uterus. FASEB J 28:230-43 (2014). [Pubmed]
Related annotations: PaperBLAST

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