Transcription Factor

						

			
Accessions: T133241_1.02 (CISBP 1.02)

			
Names: Esrra, T133241_1.02;
Organisms: Mus musculus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 462
Pfam Domains:   118-185 Zinc finger, C4 type (two domains)
  264-437 Ligand-binding domain of nuclear hormone receptor
Sequence: 
(in bold interface residues)		   1 DAARRGGAAGGGGPRSPRRSGPLGPHACPPALPEPKVTSTMSSQVVGIEPLYIKAEPASP   60
  61 DSPKGSSETETEPPVTLASGPAPARCLPGHKEEEDGEGAGSGEQGSGKLVLSSLPKRLCL  120
 121 VCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCL  180
 181 RVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAPVNALVSHL  240
 241 LVVEPEKLYAMPDPASPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVL  300
 301 QSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGDLGAALLQLVRRLQALRL  360
 361 EREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRL  420
 421 LLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD
Interface Residues: 128, 130, 137, 140, 141, 144, 145, 169, 191, 193, 195, 198, 200, 204, 206, 387, 388, 391
3D-footprint Homologues: 7wnh_D, 6l6q_B, 3g9m_B, 7xvn_C, 2han_B, 8cef_H, 2a66_A, 2nll_B, 8hbm_B, 2ff0_A, 7xv6_B, 2han_A, 8rm6_A, 7prw_B, 5cbx_B, 5cbz_E, 3g6t_A, 8k4l_B
Binding Motifs: M1447_1.02 dTGACCTTg
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.