Transcription Factor

Accessions: UP00270A (UniPROBE 20160601)
Names: "MSS1, Nrg1, Transcriptional regulator NRG1, YD5112.01C, YDR043C, Zinc finger protein MSS1"
Organisms: Saccharomyces cerevisiae
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q03125
Description: Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline p...
Length: 108
Pfam Domains: 51-73 Zinc finger, C2H2 type
51-69 C2H2-type zinc finger
65-91 Zinc-finger double domain
79-103 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 SIIQQPENGIVSNDAYNKMANSRYSLKTRKQRTDPRNTLSDEEDLEQRRKYICKICARGF 60
61 TTSGHLARHNRIHTGEKNHCCPYKGCTQRFSRHDNCLQHYRTHLKKGQ
Interface Residues: 39, 41, 42, 45, 61, 62, 63, 64, 65, 67, 68, 69, 72, 91, 92, 93, 94, 95, 97, 98, 99, 100, 102
3D-footprint Homologues: 5kl3_A, 2jpa_A, 1g2f_F, 7ysf_A, 7w1m_H, 6jnm_A, 8cuc_F, 7y3l_A, 6ml4_A, 3uk3_C, 7n5w_A, 2kmk_A, 7txc_E, 6e94_A, 5kkq_D, 6wmi_A, 5yj3_D, 4x9j_A, 2i13_A, 8ssq_A, 1llm_D, 1ubd_C, 5ei9_F, 8ssu_A, 1mey_C, 5und_A, 2drp_D, 8gn3_A, 1f2i_J, 6blw_A, 5k5i_A, 6u9q_A, 2gli_A, 7eyi_G, 5v3j_F, 4m9v_C, 8h9h_G, 2lt7_A, 1tf6_A, 1tf3_A, 7y3m_I, 6a57_A, 2wbs_A
Binding Motifs: UP00270A_1 ytvrrymAGGGTCCwwbgcw
Binding Sites: AAGGGTCC
AAGGGTCT
AGACCCTG
AGGACCCT
AGGGGTCC
AGGGTCCA
AGGGTCCC
AGGGTCCG
AGGGTCTA
CAGGGACC
CAGGGTCC
CAGGGTTC
GACCCTGA
GGACCCTA
GGGGTCCA
AAGACCCT
AAGGGACC
AAGGGTTC
AGGGCCCT
AGGGTCTC
Publications: *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.