Transcription Factor
| Accessions: | UP00270A (UniPROBE 20160601) |
| Names: | "MSS1, Nrg1, Transcriptional regulator NRG1, YD5112.01C, YDR043C, Zinc finger protein MSS1" |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q03125 |
| Description: | Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline p... |
| Length: | 108 |
| Pfam Domains: | 51-73 Zinc finger, C2H2 type 51-69 C2H2-type zinc finger 65-91 Zinc-finger double domain 79-103 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 SIIQQPENGIVSNDAYNKMANSRYSLKTRKQRTDPRNTLSDEEDLEQRRKYICKICARGF 60 61 TTSGHLARHNRIHTGEKNHCCPYKGCTQRFSRHDNCLQHYRTHLKKGQ |
| Interface Residues: | 39, 41, 42, 45, 61, 62, 63, 64, 65, 67, 68, 69, 72, 91, 92, 93, 94, 95, 97, 98, 99, 100, 102 |
| 3D-footprint Homologues: | 5kl3_A, 2jpa_A, 7w1m_H, 6jnm_A, 8cuc_F, 7y3l_A, 6ml4_A, 3uk3_C, 7n5w_A, 2kmk_A, 1g2f_F, 7ysf_A, 2i13_A, 8ssq_A, 1llm_D, 1ubd_C, 5ei9_F, 8ssu_A, 1mey_C, 5und_A, 2drp_D, 8gn3_A, 1f2i_J, 6blw_A, 5k5i_A, 6u9q_A, 2gli_A, 7txc_E, 6e94_A, 5kkq_D, 6wmi_A, 5yj3_D, 4x9j_A, 7eyi_G, 5v3j_F, 4m9v_C, 8h9h_G, 1tf3_A, 7y3m_I, 2lt7_A, 1tf6_A, 6a57_A, 2wbs_A |
| Binding Motifs: | UP00270A_1 ytvrrymAGGGTCCwwbgcw |
| Binding Sites: | AAGGGTCC AAGGGTCT AGACCCTG AGGACCCT AGGGGTCC AGGGTCCA AGGGTCCC AGGGTCCG AGGGTCTA CAGGGACC CAGGGTCC CAGGGTTC GACCCTGA GGACCCTA GGGGTCCA AAGACCCT AAGGGACC AAGGGTTC AGGGCCCT AGGGTCTC |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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