Transcription Factor
| Accessions: | DLX3_MOUSE (HOCOMOCO 10), Q64205 (JASPAR 2024) |
| Names: | DLX3_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 287 |
| Pfam Domains: | 27-106 Homeobox protein distal-less-like N terminal 130-186 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESTVTDLGYYSAPQHDYYSGQPYGQTV 60 61 NPYTYHHQFNLNGLAGTGAYSPKSEYTYGGSYRQYGAYREQPLPAQDPVSVKEEPEAEVR 120 121 MVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNR 180 181 RSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARNPLPPPLPYSAS 240 241 PNYLDDPTNSWYHTQNLSGPHLQQQPPQPATLHHASPGPPPNPGAVY |
| Interface Residues: | 130, 131, 132, 133, 171, 172, 174, 175, 178, 179, 182, 183, 186 |
| 3D-footprint Homologues: | 1fjl_B, 5zjt_E, 2h1k_B, 1puf_A, 1ig7_A, 6a8r_A, 3cmy_A, 1mnm_C, 3d1n_M, 5zfz_A, 2lkx_A, 1nk2_P, 1zq3_P, 6m3d_C, 7q3o_C, 6es3_K, 2ld5_A, 4j19_B, 3a01_E, 7psx_B, 1b72_A, 5hod_A, 3lnq_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1jgg_B, 4xrs_G, 2hos_A, 4cyc_A, 1au7_A, 5flv_I, 1le8_A, 7xrc_C, 1e3o_C, 2xsd_C, 1o4x_A, 8g87_X, 4qtr_D, 1du0_A, 1puf_B, 1k61_B, 3l1p_A |
| Binding Motifs: | MA0880.1 syAATTAm DLX3_MOUSE.H10MO.C|M01052 gmTAATTrsw PH0022.1 kmrmdaTAATTAcmswm MA0880.2 yAATTA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
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