Transcription Factor
Accessions: | 2hap_C (3D-footprint 20231221) |
Names: | CYP1 activatory protein, HAP1_YEASX, HEME ACTIVATOR PROTEIN, Heme activator protein 1, Heme-responsive zinc finger transcription factor HAP1 |
Organisms: | Saccharomyces cerevisiae |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P0CS82 |
Length: | 76 |
Pfam Domains: | 10-43 Fungal Zn(2)-Cys(6) binuclear cluster domain |
Sequence: (in bold interface residues) | 1 RKRNRIPLRCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAEEAEKELLKDNEL 60 61 KKLRERVKSLEKTLSK |
Interface Residues: | 16, 17, 18, 19, 21, 22 |
3D-footprint Homologues: | 1hwt_C, 1pyi_A, 3coq_A, 6gys_C, 1zme_D, 7uik_T, 1d66_B, 7n5w_A |
Binding Motifs: | 2hap_CD CGCtntTATCGC |
Publications: | King D.A, Zhang L, Guarente L, Marmorstein R. Structure of HAP1-18-DNA implicates direct allosteric effect of protein-DNA interactions on transcriptional activation. Nature structural biology 6:22-7 (1999). [Pubmed] |
Related annotations: | PaperBLAST |
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