Transcription Factor

Accessions: 4hc7_B (3D-footprint 20231221)
Names: GATA-binding factor 3, GATA3_HUMAN, Trans-acting T-cell-specific transcription factor GATA-3
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P23771
Length: 97
Pfam Domains: 6-39 GATA zinc finger
49-81 GATA zinc finger
Sequence:
(in bold interface residues)
1 HMGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKGTSCANCQTTTTTLW 60
61 RRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRN
Interface Residues: 15, 16, 18, 28, 32, 58, 59, 61, 71, 75, 76, 79, 96
3D-footprint Homologues: 3vd6_C, 4hc9_A, 3dfx_B, 1gat_A, 4gat_A
Binding Motifs: 4hc7_B aTCAntGATAA
Binding Sites: 4hc7_Y
4hc7_Z
Publications: Chen Y, Bates D.L, Dey R, Chen P.H, Machado A.C, Laird-Offringa I.A, Rohs R, Chen L. DNA binding by GATA transcription factor suggests mechanisms of DNA looping and long-range gene regulation. Cell reports 2:1197-206 (2012). [Pubmed]
Related annotations: PaperBLAST

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