Transcription Factor

Accessions: T127989_1.02 (CISBP 1.02), T23018 (AthalianaCistrome v4_May2016), Q84K00 (JASPAR 2024)
Names: NAC2, T127989_1.02;, AT5G04410, T23018;, ANAC078, NAC domain-containing protein 78, NAC78_ARATH, Protein NTM1-like 11
Organisms: Arabidopsis thaliana
Libraries: CISBP 1.02 1, AthalianaCistrome v4_May2016 2, JASPAR 2024 3
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:PBM, family:NAC/NAM, ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:NAC
Length: 567
Pfam Domains: 9-136 No apical meristem (NAM) protein
Sequence:
(in bold interface residues)
1 MGRGSVTSLAPGFRFHPTDEELVRYYLKRKVCNKPFKFDAISVTDIYKSEPWDLPDKSKL 60
61 KSRDLEWYFFSMLDKKYSNGSKTNRATEKGYWKTTGKDREIRNGSRVVGMKKTLVYHKGR 120
121 APRGERTNWVMHEYRLSDEDLKKAGVPQEAYVLCRIFQKSGTGPKNGEQYGAPYLEEEWE 180
181 EDGMTYVPAQDAFSEGLALNDDVYVDIDDIDEKPENLVVYDAVPILPNYCHGESSNNVES 240
241 GNYSDSGNYIQPGNNVVDSGGYFEQPIETFEEDRKPIIREGSIQPCSLFPEEQIGCGVQD 300
301 ENVVNLESSNNNVFVADTCYSDIPIDHNYLPDEPFMDPNNNLPLNDGLYLETNDLSCAQQ 360
361 DDFNFEDYLSFFDDEGLTFDDSLLMGPEDFLPNQEALDQKPAPKELEKEVAGGKEAVEEK 420
421 ESGEGSSSKQDTDFKDFDSAPKYPFLKKTSHMLGAIPTPSSFASQFQTKDAMRLHAAQSS 480
481 GSVHVTAGMMRISNMTLAADSGMGWSYDKNGNLNVVLSFGVVQQDDAMTASGSKTGITAT 540
541 RAMLVFMCLWVLLLSVSFKIVTMVSAR
Interface Residues: 77, 82, 84, 93, 95, 97, 117, 121, 122, 123, 126
3D-footprint Homologues: 7xp3_B, 3swp_A
Binding Motifs: M1404_1.02 tarCAmGccAva
M0634 CTTGttsyvCAAGaAA
M0651 CTTGttsyrCAAGaAAc
MA1677.1 haCAAGAAAcmw
MA1677.2 CAAGAAA
Binding Sites: MA1677.2.11 / MA1677.2.19
MA1677.1.1
MA1677.1.10 / MA1677.1.8
MA1677.1.11 / MA1677.1.9
MA1677.1.11 / MA1677.1.12
MA1677.1.13
MA1677.1.12 / MA1677.1.14
MA1677.1.13 / MA1677.1.15
MA1677.1.14 / MA1677.1.16
MA1677.1.15 / MA1677.1.17
MA1677.1.16 / MA1677.1.18
MA1677.1.17 / MA1677.1.19
MA1677.1.2
MA1677.1.20
MA1677.1.2 / MA1677.1.3
MA1677.1.3 / MA1677.1.4
MA1677.1.5
MA1677.1.4 / MA1677.1.6
MA1677.1.5 / MA1677.1.7
MA1677.1.6 / MA1677.1.8
MA1677.1.7 / MA1677.1.9
MA1677.1.18
MA1677.1.19
MA1677.1.10
MA1677.1.20
MA1677.2.13 / MA1677.2.14 / MA1677.2.4 / MA1677.2.8
MA1677.2.17 / MA1677.2.2
MA1677.2.1 / MA1677.2.12 / MA1677.2.15 / MA1677.2.16 / MA1677.2.18 / MA1677.2.20 / MA1677.2.3 / MA1677.2.5 / MA1677.2.6 / MA1677.2.9
MA1677.2.10
MA1677.2.7
Publications: Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Related annotations: PaperBLAST

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