Transcription Factor

Accessions: Q9V472 (JASPAR 2024)
Names: DLim1, GH04929p, LIM homeobox 1, isoform A, Q9V472_DROME
Organisms: Drosophila melanogaster
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9V472
Length: 505
Pfam Domains: 27-81 LIM domain
86-142 LIM domain
248-304 Homeobox domain
270-300 Homeobox KN domain
Sequence:
(in bold interface residues)
1 MAFGAVLHTSQHNIGRSEPPVGVGDPCAGCNKPILDKFLLNVLERAWHASCVRCCECLQP 60
61 LTDKCFSRESKLYCRNDFFRRYGTKCSGCGQGIAPSDLVRKPRDKVFHLNCFTCCICRKQ 120
121 LSTGEQLYVLDDNKFICKDDYLLGKAPSCGHNSLSDSLMGSASEDDDDDDPPHLRATALG 180
181 LGVLGPNGPDSAGGPLGTSDISVQSMSTDSKNTHDDSDQGSLDGDPDGRGDSQAENKSPD 240
241 DANGSKRRGPRTTIKAKQLEVLKTAFNQTPKPTRHIREQLAKETGLPMRVIQVWFQNKRS 300
301 KERRMKQITSMGRPPFFGGARKMRGFPMNLSPGGLDDGPGFPYFAADAKFEFGYGGPFHP 360
361 HDGPYFPGHPGGPMPFNAPGGPMDHSGPIPMVNEFGLTPEATFLGQAGGPPMQLQSAVGP 420
421 PPPPPPPSAEHLMAAAAAAAQQQAAQQQQQQQQQQQQQQQQNAQQAANQTQQQQQQNGPR 480
481 TNSPEFMSSANFSEPQNMQNEGLVW
Interface Residues: 232, 235, 236, 239, 247, 248, 249, 250, 251, 289, 290, 292, 293, 296, 297, 300, 301, 303, 304
3D-footprint Homologues: 5zfz_A, 2ld5_A, 4j19_B, 3a01_E, 6wig_A, 1ig7_A, 2lkx_A, 1puf_A, 5zjt_E, 3cmy_A, 1fjl_B, 6a8r_A, 3d1n_M, 7psx_B, 1zq3_P, 1nk2_P, 5jlw_D, 1b72_A, 4cyc_A, 4xrs_G, 3l1p_A, 2h1k_B, 1jgg_B, 6m3d_C, 5flv_I, 3lnq_A, 2hdd_A, 1au7_A, 5hod_A, 3rkq_B, 2r5y_A, 1puf_B, 2hos_A, 2xsd_C, 7q3o_C, 7xrc_C, 1e3o_C, 1le8_A, 6es3_K, 1o4x_A, 1du0_A, 4qtr_D, 8g87_X, 4xrm_B
Binding Motifs: MA0194.1 TTAATTA
Binding Sites: MA0194.1.10
MA0194.1.20
MA0194.1.16
MA0194.1.9
MA0194.1.13
MA0194.1.1
MA0194.1.11
MA0194.1.12
MA0194.1.14
MA0194.1.15
MA0194.1.17
MA0194.1.18
MA0194.1.19
MA0194.1.2
MA0194.1.3
MA0194.1.4
MA0194.1.5
MA0194.1.6
MA0194.1.7
MA0194.1.8
Publications: Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.