Transcription Factor

						

			
Accessions: 6pmi_F (3D-footprint 20231221)

			
Names: FLIA_ECOLI, RNA polymerase sigma factor FliA, RNA polymerase sigma factor for flagellar operon, Sigma-27, Sigma-28
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P0AEM6
Length: 239
Pfam Domains:     15-87 Sigma-70 region 2 
   95-165 Sigma-70 region 3
  178-231 Sigma-70, region 4
  184-232 Sigma-70, region 4
Sequence: 
(in bold interface residues)		   1 NSLYTAEGVMDKHSLWQRYVPLVRHEALRLQVRLPASVELDDLLQAGGIGLLNAVERYDA   60
  61 LQGTAFTTYAVQRIRGAMLDELRSRDWVPRSVRRNAREVAQAIGQLEQELGRNATETEVA  120
 121 ERLGIDIADYRQMLLDTNNSQLFSYDEWREEHGDSIELVTDDHQRENPLQQLLDSNLRQR  180
 181 VMEAIETLPEREKLVLTLYYQEELNLKEIGAVLEVGESRVSQLHSQAIKRLRTKLGKLL
Interface Residues: 81, 206, 207, 216, 217, 218, 219, 221, 222, 224
3D-footprint Homologues: 5h3r_A, 3n97_A, 6jhe_A, 2h27_A, 8cyf_B
Binding Motifs: 6pmi_F TgnGATaACGAGAT
Binding Sites: 6pmi_1
6pmi_2
			
Publications: Shi W, Zhou W, Zhang B, Huang S, Jiang Y, Schammel A, Hu Y, Liu B. Structural basis of bacterial σ(28) -mediated transcription reveals roles of the RNA polymerase zinc-binding domain. EMBO J : (2020). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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