Transcription Factor

Accessions: Q8IGP5 (JASPAR 2024)
Names: Chromatin-linked adaptor for MSL proteins, isoform B, Q8IGP5_DROME, RE54188p
Organisms: Drosophila melanogaster
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q8IGP5
Length: 566
Pfam Domains: 127-149 C2H2-type zinc finger
127-149 C2H2-type zinc finger
127-149 Zinc finger, C2H2 type
365-387 Zinc finger, C2H2 type
365-388 C2H2-type zinc finger
365-387 C2H2-type zinc finger
379-403 Zinc-finger double domain
393-415 Zinc finger, C2H2 type
408-431 Zinc-finger double domain
420-431 C2H2-type zinc finger
421-443 Zinc finger, C2H2 type
421-443 C2H2-type zinc finger
435-459 Zinc-finger double domain
449-471 Zinc finger, C2H2 type
449-469 C2H2-type zinc finger
449-471 C2H2-type zinc finger
464-487 Zinc-finger double domain
477-499 Zinc finger, C2H2 type
477-499 C2H2-type zinc finger
491-515 Zinc-finger double domain
505-524 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MEDLTKNIIFTNAINGQPATIQYQTADGTILKQPKIEGQKTEQQPTFYYTTNGNGGTVNL 60
61 AQLATTDDNKTCYIAQPVGGYNYALVNGMPLNQGAALGIATVDAQGRIQIVNQNKPIAAN 120
121 TISNISFKCDVCSDMFPHLALLNAHKRMHTDGEQQQQQQHNAQAGGDSIAVVSAQGLVQA 180
181 QNIIGNGQMGQIQIVSSDTLEPVQQSVMQQQQHESKASKCINCGSSMLQQSKRKGPKQVR 240
241 CESCMQAEQTAQQQQQLFVAQDGQMAHPVQIISTTPQAQAQLQQIVAAQTGGTTPKREAS 300
301 SGSGHHPVKKRNSQQMTKCQKCNGSGVVLVGQHSHASHSGVGGSVKQSVTVKTECLSCRN 360
361 PSKPFSCNICGGLFSRYSSLWSHKKLHSGEKNYKCSICGLAFAKAVYLKNHARIHTGEKP 420
421 YKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIHTGEKPYKCE 480
481 ICGSAFSQAAHLKNHAKVHSGEKPYKCEICSAAFADRFALKRHRGIHQKYGQTAPRQTSS 540
541 DGMIVHKQEIPDMEDEAQQEVIIGGL
Interface Residues: 365, 376, 377, 378, 379, 381, 382, 384, 385, 388, 403, 404, 405, 406, 407, 409, 410, 431, 432, 433, 434, 435, 437, 438, 457, 459, 460, 461, 462, 463, 464, 466, 467, 469, 487, 488, 489, 490, 491, 492, 493, 494, 495, 498, 516, 517, 518, 519, 521, 522
3D-footprint Homologues: 2kmk_A, 5v3j_F, 8ssq_A, 7w1m_H, 6blw_A, 5yel_A, 8ssu_A, 2jpa_A, 1ubd_C, 7n5w_A, 6jnm_A, 3uk3_C, 1tf3_A, 1tf6_A, 5ei9_F, 5kl3_A, 5k5i_A, 8h9h_G, 6e94_A, 7ysf_A, 2lt7_A, 8cuc_F, 5kkq_D, 6ml4_A, 2drp_D, 2wbs_A, 8gn3_A, 1g2f_F, 7txc_E, 6u9q_A, 4x9j_A, 2gli_A, 1f2i_J, 4m9v_C, 7y3m_I, 6a57_A, 7y3l_A, 1llm_D, 5k5l_F, 5yj3_D
Binding Motifs: MA1700.1 GwGmGAGCGAGAgr
Binding Sites: MA1700.1.1
MA1700.1.10
MA1700.1.11
MA1700.1.12
MA1700.1.13
MA1700.1.14
MA1700.1.15
MA1700.1.16 / MA1700.1.6
MA1700.1.17
MA1700.1.18
MA1700.1.19
MA1700.1.2
MA1700.1.20
MA1700.1.3
MA1700.1.4
MA1700.1.5
MA1700.1.7
MA1700.1.8
MA1700.1.9
Publications: Soruco MM, Chery J, Bishop EP, Siggers T, Tolstorukov MY, Leydon AR, Sugden AU, Goebel K, Feng J, Xia P, Vedenko A, Bulyk ML, Park PJ, Larschan E. The CLAMP protein links the MSL complex to the X chromosome during Drosophila dosage compensation. Genes Dev 27:1551-6 (2013). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.