Transcription Factor

						

			
Accessions: 5zko_A (3D-footprint 20231221), 5zko_C (3D-footprint 20231221)

			
Names: cAMP-responsive element-binding protein 1, CREB-1, CREB1_HUMAN, Cyclic AMP-responsive element-binding protein 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P16220
Length: 53
Pfam Domains:      1-52 bZIP transcription factor
     3-49 Basic region leucine zipper
Sequence: 
(in bold interface residues)		   1 KREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYC
Interface Residues: 5, 9, 10, 12, 13, 16, 17
3D-footprint Homologues: 4eot_A, 2wt7_B, 5t01_B, 1dh3_C, 5vpe_D, 7x5e_F
Binding Motifs: 5zko_ACGH GCTGACGTCAGC
Binding Sites: 5zko_B / 5zko_D
			
Publications: Song Y, Zhai L, Valencia Swain J, Chen Y, Wang P, Chen L, Liu Y, Xiang S. Structural Insights into the CRTC2-CREB Complex Assembly on CRE. J Mol Biol 430:1926-1939 (2018). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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