Transcription Factor

Accessions: ZNF415 (humanC2H2ZF-ChIP Feb2015)
Names: ENSG00000170954, Q09FC8, ZNF415
Organisms: Homo sapiens
Libraries: humanC2H2ZF-ChIP Feb2015 1
1 Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. C2H2 zinc finger proteins greatly expand the human regulatory lexicon. Nat Biotechnol 33:555-62 (2015). [Pubmed]
Notes: TF family: C2H2 experiment: ChIP-seq/MEME/B1H-RC
Length: 603
Pfam Domains: 284-302 Zinc-finger double domain
292-314 C2H2-type zinc finger
292-314 Zinc finger, C2H2 type
292-302 C2H2-type zinc finger
306-331 Zinc-finger double domain
319-330 C2H2-type zinc finger
320-342 C2H2-type zinc finger
320-342 Zinc finger, C2H2 type
337-359 Zinc-finger double domain
348-370 Zinc finger, C2H2 type
348-370 C2H2-type zinc finger
365-386 Zinc-finger double domain
375-386 C2H2-type zinc finger
376-398 Zinc finger, C2H2 type
376-396 C2H2-type zinc finger
391-414 Zinc-finger double domain
403-424 C2H2-type zinc finger
404-426 C2H2-type zinc finger
404-426 Zinc finger, C2H2 type
419-442 Zinc-finger double domain
431-445 C2H2-type zinc finger
432-454 C2H2-type zinc finger
432-454 Zinc finger, C2H2 type
446-471 Zinc-finger double domain
459-482 C2H2-type zinc finger
460-482 C2H2-type zinc finger
460-482 Zinc finger, C2H2 type
474-498 Zinc-finger double domain
487-506 C2H2-type zinc finger
488-508 C2H2-type zinc finger
488-510 Zinc finger, C2H2 type
502-526 Zinc-finger double domain
515-534 C2H2-type zinc finger
516-536 C2H2-type zinc finger
516-538 Zinc finger, C2H2 type
530-554 Zinc-finger double domain
543-563 C2H2-type zinc finger
544-566 C2H2-type zinc finger
544-566 Zinc finger, C2H2 type
558-582 Zinc-finger double domain
571-591 C2H2-type zinc finger
572-594 Zinc finger, C2H2 type
572-594 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MPELYTEDFIQGCDVGELQEPGLPGVLSYVGAQERALDHRKPSTSSKKTKRVEIDQRCEN 60
61 RLECNGAISAHCNLRLPDSNDSPASASRVAGITDLSRNCVIKELAPQQEGNPGEVFHTVT 120
121 LEQHEKHDIEEFCFREIKKKIHDFDCQWRDDERNCNKVTTAPKENLTCRRDQRDRRGIGN 180
181 KSIKHQLGLSFLPHPHELQQFQAEGKIYECNHVEKSVNHGSSVSPPQIISSTIKTHVSNK 240
241 YGTDFICSSLLTQEQKSCIREKPYRYIECDKALNHGSHMTVRQVSHSGEKGYKCDLCGKV 300
301 FSQKSNLARHWRVHTGEKPYKCNECDRSFSRNSCLALHRRVHTGEKPYKCYECDKVFSRN 360
361 SCLALHQKTHIGEKPYTCKECGKAFSVRSTLTNHQVIHSGKKPYKCNECGKVFSQTSSLA 420
421 THQRIHTGEKPYKCNECGKVFSQTSSLARHWRIHTGEKPYKCNECGKVFSYNSHLASHRR 480
481 VHTGEKPYKCNECGKAFSVHSNLTTHQVIHTGEKPYKCNQCGKGFSVHSSLTTHQVIHTG 540
541 EKPYKCNECGKSFSVRPNLTRHQIIHTGKKPYKCSDCGKSFSVRPNLFRHQIIHTKEKPY 600
601 KRN
Interface Residues: 303, 304, 305, 306, 308, 309, 330, 331, 332, 333, 334, 337, 341, 359, 360, 361, 362, 365, 376, 387, 388, 389, 390, 393, 414, 415, 416, 417, 418, 420, 421, 422, 423, 424, 427, 442, 443, 444, 445, 446, 447, 448, 449, 450, 453, 470, 471, 472, 473, 474, 476, 477, 479, 498, 499, 500, 501, 502, 505, 509, 511, 525, 526, 527, 528, 529, 530, 532, 533, 537, 554, 555, 556, 557, 558, 560, 561, 583, 585, 586, 589
3D-footprint Homologues: 2drp_D, 5k5i_A, 7w1m_H, 5und_A, 2gli_A, 5k5l_F, 8ssu_A, 5kkq_D, 8ssq_A, 5yel_A, 5v3j_F, 2i13_A, 6wmi_A, 1ubd_C, 2kmk_A, 7ysf_A, 8cuc_F, 7n5w_A, 3uk3_C, 6jnm_A, 1llm_D, 6blw_A, 6u9q_A, 1mey_C, 4m9v_C, 7eyi_G, 8h9h_G, 7y3m_I, 6e94_A, 6a57_A, 2jpa_A, 1tf6_A, 4x9j_A, 2wbs_A, 5ei9_F, 7txc_E, 5kl3_A, 1f2i_J, 5yj3_D, 2lt7_A, 7y3l_A, 1tf3_A, 1g2f_F, 6ml4_A, 8gn3_A
Binding Motifs: ZNF415_ChIP gGrygmTgGAGCcrg
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.