Transcription Factor
| Accessions: | UP00003A (UniPROBE 20160601) |
| Names: | E2F transcription factor 3, E2F-3, E2F3, E2f3a, E2F3b, mKIAA0075, Transcription factor E2F3 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | O35261 |
| Description: | E2F transcription factor 3 |
| Length: | 96 |
| Pfam Domains: | 16-81 E2F/DP family winged-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 SPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDIT 60 61 NVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQG |
| Interface Residues: | 16, 52, 53, 54, 55, 57 |
| 3D-footprint Homologues: | 1cf7_A, 4yo2_A, 1cf7_B |
| Binding Motifs: | UP00003A_1 rhwArGGCGCGCshw UP00003A_2 msywyGGCGCCAmrmgs |
| Binding Sites: | AAGCGCGC ACGCGCGC AGCGCGCG AGGGCGCC ATGGCGCC ATGGCGCG CGCGCCAA CGCGCGCC CGCGCGCG CGGCGCCA GCGCCAAA GCGCCATA GCGCGCCA GCGCGCGC GGCGCCAA GGCGCCCA GGCGCGCA GGCGCGCC GGGCGCCA TGGCGCCA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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