Transcription Factor

Accessions: 6ki6_B (3D-footprint 20231221)
Names: B-cell CLL/lymphoma 11A, B-cell lymphoma/leukemia 11A, BC11A_HUMAN, BCL-11A, COUP-TF-interacting protein 1, Ecotropic viral integration site 9 protein homolog, EVI-9, Zinc finger protein 856
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q9H165
Length: 52
Pfam Domains: 2-23 Zinc finger, C2H2 type
3-23 C2H2-type zinc finger
15-39 Zinc-finger double domain
29-51 C2H2-type zinc finger
29-51 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 DTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHG
Interface Residues: 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 24, 26, 35, 39, 40, 41, 42, 43, 44, 45, 46, 47, 50
3D-footprint Homologues: 3uk3_C, 7ysf_A, 2kmk_A, 6jnm_A, 8cuc_F, 7y3l_A, 7n5w_A, 5ei9_F, 1tf3_A, 5kl3_A, 8ssu_A, 2drp_D, 1g2f_F, 6wmi_A, 5k5i_A, 8gn3_A, 7w1m_H, 5und_A, 2gli_A, 1llm_D, 5k5l_F, 2lt7_A, 1ubd_C, 6ml4_A, 5v3j_F, 4x9j_A, 1mey_C, 6blw_A, 5kkq_D, 8ssq_A, 1f2i_J, 6u9q_A, 7txc_E, 4m9v_C, 7eyi_G, 8h9h_G, 6e94_A, 2i13_A, 7y3m_I, 8gh6_A, 6a57_A, 8edg_C, 2jpa_A, 1yuj_A, 5yj3_D, 1tf6_A, 2wbs_A, 5yel_A
Binding Motifs: 6ki6_B TGGTCAag
Binding Sites: 6ki6_F
6ki6_E
Publications: Yang Y, Xu Z, He C, Zhang B, Shi Y, Li F. Structural insights into the recognition of γ-globin gene promoter by BCL11A. Cell Res 29:960-963 (2019). [Pubmed]
Related annotations: PaperBLAST

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