Transcription Factor

Accessions: T133930_1.02 (CISBP 1.02)
Names: RORC, T133930_1.02;
Organisms: Tetraodon nigroviridis
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 452
Pfam Domains: 16-84 Zinc finger, C4 type (two domains)
237-419 Ligand-binding domain of nuclear hormone receptor
Sequence:
(in bold interface residues)
1 LFIFFCASPAQIEVIPCKICGDKSSGVHYGVITCEGCKGFFRRSQLPTVSYSCSRQSNCQ 60
61 IDRASRNRCQHCRLQKCLAQGMSRDAVKFGRMSKRQRDSLIAEVERHPKTRQDRATQLLQ 120
121 PAYSFTGENELMPYAADVHPYLFCSPNESQVSNMIYRGTGVSPVSRSQGRGDSGGHPDPS 180
181 HVLVASFPYNPLENRYTFYPHSLRNTDELCASIVRAHRETSQWRVEELQGLRWKLFSREE 240
241 IQAYQSKSVDEMWQHCAIRLTDAVQYVVEFAKHIPGFRMLTQNDQIALLKTGSMEVVLVR 300
301 MSRFFNTENNTVYFDGKFAGADLFKSLACGDLITAVFDFAHDMCALKLSEHQLALFSALV 360
361 LINTDRPCLEDRGKVQRVQRTVELGLRHILQKDNQEGLMAKLYQKMAVLRSLCSLHMEKL 420
421 RWFSQRYPLTVHSLFPPLYKELFTSEADLLPG
Interface Residues: 25, 26, 28, 29, 35, 36, 38, 39, 42, 43, 67, 89, 91, 92, 94, 96, 220
3D-footprint Homologues: 6fbq_A, 7wnh_D, 6l6q_B, 1a6y_A, 3g9m_B, 1lo1_A, 4oln_B, 1kb2_B, 8hbm_B, 5krb_G, 2han_B, 1lat_A, 2a66_A, 1dsz_A, 2nll_B, 7xv6_B, 2ff0_A, 1hcq_E, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 7prw_B, 5cbx_B, 3g6t_A, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B, 1r4i_A, 5emc_A, 1wte_A
Binding Motifs: M1459_1.02 rsTGACCTCk
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.