Transcription Factor
| Accessions: | ZIC2_HUMAN (HOCOMOCO 10), ZIC2 (humanC2H2ZF-ChIP Feb2015) |
| Names: | ZIC2_HUMAN, Zinc finger protein of the cerebellum 2, Zinc finger protein ZIC 2, ENSG00000043355, O95409, ZIC2 |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1, humanC2H2ZF-ChIP Feb2015 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. C2H2 zinc finger proteins greatly expand the human regulatory lexicon. Nat Biotechnol 33:555-62 (2015). [Pubmed] |
| Uniprot: | O95409 |
| Notes: | TF family: C2H2 experiment: ChIP-seq/MEME/B1H-RC |
| Length: | 532 |
| Pfam Domains: | 273-291 C2H2-type zinc finger 320-345 Zinc-finger double domain 333-357 Zinc finger, C2H2 type 333-357 C2H2-type zinc finger 349-376 Zinc-finger double domain 363-387 C2H2-type zinc finger 381-404 Zinc-finger double domain 393-415 C2H2-type zinc finger 393-415 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MLLDAGPQFPAIGVGSFARHHHHSAAAAAAAAAEMQDRELSLAAAQNGFVDSAAAHMGAF 60 61 KLNPGAHELSPGQSSAFTSQGPGAYPGSAAAAAAAAALGPHAAHVGSYSGPPFNSTRDFL 120 121 FRSRGFGDSAPGGGQHGLFGPGAGGLHHAHSDAQGHLLFPGLPEQHGPHGSQNVLNGQMR 180 181 LGLPGEVFGRSEQYRQVASPRTDPYSAAQLHNQYGPMNMNMGMNMAAAAAHHHHHHHHHP 240 241 GAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGPEQSNH 300 301 VCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGE 360 361 KPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSPQ 420 421 GSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGGGS 480 481 GSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSSNFNEWYV |
| Interface Residues: | 278, 279, 281, 282, 285, 315, 316, 317, 318, 319, 322, 326, 345, 346, 347, 348, 349, 351, 352, 353, 354, 355, 357, 358, 361, 375, 376, 377, 378, 379, 380, 381, 382, 383, 386, 403, 404, 405, 406, 407, 408, 409, 410, 411, 434, 435 |
| 3D-footprint Homologues: | 5v3j_F, 1ubd_C, 7n5w_A, 1tf3_A, 7w1m_H, 8cuc_F, 5kkq_D, 5ei9_F, 2gli_A, 8ssq_A, 1tf6_A, 8ssu_A, 6ml4_A, 4x9j_A, 8gn3_A, 7eyi_G, 6e94_A, 7ysf_A, 6wmi_A, 5k5i_A, 2i13_A, 5und_A, 3uk3_C, 6jnm_A, 7y3l_A, 1mey_C, 6blw_A, 6u9q_A, 5yel_A, 2kmk_A, 5kl3_A, 1g2f_F, 1llm_D, 2v6e_B, 8h9h_G, 7y3m_I, 2lt7_A, 6a57_A, 2jpa_A, 2wbs_A, 2drp_D, 1f2i_J, 7txc_E, 5yj3_D, 5k5l_F, 4m9v_C |
| Binding Motifs: | ZIC2_HUMAN.H10MO.C|M01617 kGGGtGGTc ZIC2_ChIP cyCCTGCtGrg |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.